[1830–40; pyrophosph(oricacid) + -ate2]This word is first recorded in the period 1830–40. Other words that entered Englishat around the same time include: baby talk, isomerism, orientation, showcase, walkover
Examples of 'pyrophosphate' in a sentence
pyrophosphate
Microcrystal-line deposition most often consists of calcium pyrophosphate dehydrate crystals and/or hydroxyapatite crystals.
Teruyuki Takahashi, Yugo Minakata, Masato Tamura, Toshiaki Takasu, Marohito Murakami 2013, 'A Rare Case of Crowned Dens Syndrome Mimicking Aseptic Meningitis', Case Reports in Neurologyhttp://www.karger.com/Article/FullText/348745. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These are discussed by dividing the pyrophosphate crystals into three structural units.
Redouane Khaoulaf, Puja Adhikari, Mohamed Harcharras, Khalid Brouzi, Hamid Ez-Zahraouy,Wai-Yim Ching 2019, 'Atomic-Scale Understanding of Structure and Properties of Complex Pyrophosphate Crystalsby First-Principles Calculations', Applied Scienceshttps://www.mdpi.com/2076-3417/9/5/840. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Pyrophosphate was shown to participate in iron transfer from transferrin to ferritin.
Francis Biville, Christophe Brézillon, Dario Giorgini, Muhamed-Kheir Taha 2014, 'Pyrophosphate-mediated iron acquisition from transferrin in Neisseria meningitidisdoes not require TonB activity.', PLoS ONEhttp://europepmc.org/articles/PMC4189776?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In pseudogout, the mechanism underlying the deposition of calcium pyrophosphate dehydrate crystals remains unclear.
Ryosuke Sato, MD, Shunji Nakano, MD, PhD, Tomoya Takasago, MD, Masaru Nakamura, MD,Masahiro Kashima, MD, Takashi Chikawa, MD, PhD, Daisuke Hamada, MD, PhD, TomohiroGoto, MD, PhD, Koichi Sairyo, MD, PhD 2016, 'Chondrogenesis in the synovial tissue is associated with the onset of pseudogout aftertotal knee arthroplasty', Arthroplasty Todayhttp://www.sciencedirect.com/science/article/pii/S235234411500076X. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Pyrophosphate did not affect proliferation in either cell type.
Michael Pujari-Palmer, Shiuli Pujari-Palmer, Xi Lu, Thomas Lind, Håkan Melhus, ThomasEngstrand, Marjam Karlsson-Ott, Hakan Engqvist 2016, 'Pyrophosphate Stimulates Differentiation, Matrix Gene Expression and Alkaline PhosphataseActivity in Osteoblasts', PLOS ONE10.1371/journal.pone.0163530. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Pyrophosphate can also affect the resorption rate and bioactivity of orthopedic ceramics.
Michael Pujari-Palmer, Shiuli Pujari-Palmer, Xi Lu, Thomas Lind, Håkan Melhus, ThomasEngstrand, Marjam Karlsson-Ott, Hakan Engqvist 2016, 'Pyrophosphate Stimulates Differentiation, Matrix Gene Expression and Alkaline PhosphataseActivity in Osteoblasts', PLOS ONE10.1371/journal.pone.0163530. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Iron-complexing compounds like citrate and pyrophosphate have been shown to support meningococcal growth ex vivo.
Francis Biville, Christophe Brézillon, Dario Giorgini, Muhamed-Kheir Taha 2014, 'Pyrophosphate-Mediated Iron Acquisition from Transferrin in Neisseria meningitidisDoes Not Require TonB Activity', PLoS ONE10.1371/journal.pone.0107612. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Geranylgeranyl pyrophosphate and farnesyl pyrophosphate was able to block, in part, this inhibitory activity.
Shaojuan Li, Paul de Souza 2011, 'Ras Isoprenylation and pAkt Inhibition by Zoledronic Acid and Fluvastatin EnhancesPaclitaxel Activity in T24 Bladder Cancer Cells', Cancershttp://www.mdpi.com/2072-6694/3/1/662/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Microscopy of synovial fluid also identified intracellular calcium pyrophosphate crystals.
John Koo, Gregory D. Deans 2018, 'A Rare Case of Burkholderia cepacia Complex Septic Arthritis', Case Reports in Infectious Diseaseshttp://dx.doi.org/10.1155/2018/6232760. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)