any of a group of substances that cause a rise in temperature in an animal body
pyrogen in American English
(ˈpaɪrədʒən)
noun
Medicine
a substance that produces fever
Word origin
pyro- + -gen
pyrogen in American English
(ˈpairədʒən, -ˌdʒen)
noun
a substance, as a thermostable bacterial toxin, that produces a rise in temperature in a human or animal
Word origin
[1855–60; pyro- + -gen]This word is first recorded in the period 1855–60. Other words that entered Englishat around the same time include: boilerplate, kickoff, output, pickup, pipelinepyro- is a combining form meaning “fire,” “heat,” “high temperature,” used in the formationof compound words. Other words that use the affix pyro- include: pyrolusite, pyromancy; -gen is a combining form meaning “that which produces,” used in the formation of compoundwords. Other words that use the affix -gen include: endogen, hydrogen
Examples of 'pyrogen' in a sentence
pyrogen
Three batches of sera, two pyrogen free and one pyrogenic, were tested.
Carla Lilian de Agostini Utescher, Klariane Laís Buosi, Viviane Fungaro Botosso, WagnerQuintilio 2018, 'Monocyte Activation Test (MAT) as a possibility of replacement for the rabbit pyrogentest in hyperimmune sera', Brazilian Journal of Pharmaceutical Scienceshttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000200605&lng=en&tlng=en. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Furthermore, we overcame the problem of pyrogen cross-contamination using a cleaner and more efficient program.
Kang-Po Li, Ming-Kuan Hu, Cheng-Yi Cheng, Li-Fan Hsu, Ta-Kai Chou, Chyng-Yann Shiue,Daniel H Shen 2017, 'A practical and pyrogen-free preparation of 11C-L-methionine in a good manufacturingpractice-compliant approach', Journal of Medical Scienceshttp://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2017;volume=37;issue=1;spage=7;epage=11;aulast=Li. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The ultra- and nanofiltration membranes used for pyrogen-free water preparing are described.
Yu. A. Fedotov, K. A. Timakova, A. V. Tarasov, S. A. Lepeshin, Ye. S. Yavorskaya 2012, 'Polymer Membranes in Medicine and Pharmaceutics', Eurasian Chemico-Technological Journal http://ect-journal.kz/index.php/ectj/article/view/380. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The sterility and pyrogen tests are important steps to ensure the quality and safety of these immunobiological products.
Paula Gomes Santos, Dilvani Oliveira Santos, Lilia Ribeiro Seródio, Rachel de SouzaMarinho, Carlos Rangel Rodrigues, Lucio Mendes Cabral, Marcelo de Pádula, ValériaPereira de Sousa, Helena Carla Castro 2009, 'Antiophidian sera sterility control: topics in perspective', Brazilian Journal of Pharmaceutical Scienceshttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000300004. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Developments in the field of sterilizing, bacteriostatic and bactericidal membranes and membranes for pyrogen-free water preparingare considered.
Yu. A. Fedotov, K. A. Timakova, A. V. Tarasov, S. A. Lepeshin, Ye. S. Yavorskaya 2012, 'Polymer Membranes in Medicine and Pharmaceutics', Eurasian Chemico-Technological Journal http://ect-journal.kz/index.php/ectj/article/view/380. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)