a nucleoside, C10H12N4O5, formed from the attachment of hypoxanthine to a ribose ring, and which is used as a temporary source of sugar during kidney transportation
Examples of 'inosine' in a sentence
inosine
Inosine pranobex was generally well tolerated, and no deaths were reported.
Jiří Beran, Eva Šalapová, Marian Špajdel, on behalf of the Isoprinosine Study (EWOISO-2014/1) Team 2016, 'Inosine pranobex is safe and effective for the treatment of subjects with confirmedacute respiratory viral infections: analysis and subgroup analysis from a Phase 4,randomised, placebo-controlled, double-blind study', BMC Infectious Diseaseshttp://link.springer.com/article/10.1186/s12879-016-1965-5. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Adenosine and inosine reduced collagen-induced platelet adhesion and aggregate formation under flow.
Eduardo Fuentes, Jaime Pereira, Diego Mezzano, Marcelo Alarcón, Julio Caballero, IvánPalomo 2014, 'Inhibition of platelet activation and thrombus formation by adenosine and inosine:studies on their relative contribution and molecular modeling.', PLoS ONEhttp://europepmc.org/articles/PMC4231063?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Side effects of treatment with inosine pranobex were not registered.
E.N. Simovanyan, V.B. Denisenko, A.V. Grigoryan 2011, 'Efficacy of inosine pranobex in frequently ill children with chronic Epstein–Barrvirus infection: randomized study', Voprosy Sovremennoj Pediatriihttp://vsp.spr-journal.ru:80/jour/article/view/562. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Ham1p encodes an inosine triphosphate pyrophosphatase that has been implicated in resistance to purine analogues.
Mattias Carlsson, Marie Gustavsson, Guo-Zhen Hu, Eva Murén, Hans Ronne 2013, 'A Ham1p-dependent mechanism and modulation of the pyrimidine biosynthetic pathwaycan both confer resistance to 5-fluorouracil in yeast.', PLoS ONEhttp://europepmc.org/articles/PMC3792807?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Thus, inosine might be a useful therapeutic for improving outcome after spinal cord injury.
Daniel Kim, Laila Zai, Peng Liang, Colleen Schaffling, David Ahlborn, Larry I. Benowitz 2013, 'Inosine Enhances Axon Sprouting and Motor Recovery after Spinal Cord Injury', PLoS ONE10.1371/journal.pone.0081948. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Multivariate analysis revealed the most discriminative metabolites, which included inosine and glutamic acid.
Rasmus Madsen, Viqar Showkat Banday, Thomas Moritz, Johan Trygg, Kristina Lejon 2012, 'Altered Metabolic Signature in Pre-Diabetic NOD Mice', PLoS ONE10.1371/journal.pone.0035445. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The proposed system was applied to inosine determination in both pharmaceutical preparations and human serum.
Li Liu, Jun-feng Song, Peng-fei Yu, Bin Cui 2006, 'A novel electrochemical sensing system for inosine and its application for inosinedetermination in pharmaceuticals and human serum', Electrochemistry Communicationshttp://www.sciencedirect.com/science/article/pii/S1388248106002785. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These mutant spores, however, germinated efficiently when inosine was supplemented with alanine.
Tetyana Dodatko, Monique Akoachere, Stefan M Muehlbauer, Forrest Helfrich, Amber Howerton,Christian Ross, Vicki Wysocki, Jürgen Brojatsch, Ernesto Abel-Santos 2009, 'Bacillus cereus spores release alanine that synergizes with inosine to promote germination.',PLoS ONEhttp://europepmc.org/articles/PMC2712684?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A novel sensing system for monitoring inosine was proposed.
Li Liu, Jun-feng Song, Peng-fei Yu, Bin Cui 2006, 'A novel electrochemical sensing system for inosine and its application for inosinedetermination in pharmaceuticals and human serum', Electrochemistry Communicationshttp://www.sciencedirect.com/science/article/pii/S1388248106002785. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)