释义 |
pseudogene in American English (ˈsudoʊˌdʒin) noun a genelike section of DNA that has no apparent function Examples of 'pseudogene' in a sentencepseudogene Pseudogene transcription and function remain insufficiently understood.Excluding pseudogene analysis, all point mutations were detected on the training set.Deletions appear to have the largest effect on pseudogene formation and loss of regulatoryregions.Its own copy has much shortened and turned out to be a pseudogene.Here we present a computational investigation of this question based on sequence, intron-exon, synteny and pseudogene analyses.The aim of this study was to identify a prognostic pseudogene signature of osteosarcoma by machine learning.About 12% of the rice protein-coding genes, half of which are in singleton families, have a pseudogene paralog.Therefore, this species may generate antibody diversity via a gene conversion-like mechanism associated with its pseudogene reserves.Many non-coding regions including pseudogenes were mapped by multiple transcripts, indicating the generality of pseudogene transcriptions.Given the high sequence homology with the corresponding parent genes, we also discuss challenges for pseudogene research. |