the branch of immunochemistry dealing with cells and cellular activity
Derived forms
immunocytochemical (ˌimmunoˌcytoˈchemical)
adjective
immunocytochemistry in American English
(ˌimjənouˌsaitouˈkeməstri, iˌmjuː-)
noun
the detection of chemical components of cells by means of antibodies coupled to substances that can be made visible
Derived forms
immunocytochemical
adjective
immunocytochemically
adverb
Word origin
[1965–70; immuno- + cyto- + chemistry]This word is first recorded in the period 1965–70. Other words that entered Englishat around the same time include: Coriolis effect, Finlandization, T cell, stun gun, wraparoundimmuno- is a combining form representing immune or immunity in compound words. Other words that use the affix immuno- include: immunodiffusion, immunoelectrophoresis, immunoprecipitation, immunotherapy, immunotoxin; cyto- is a combining form meaning “cell,” used in the formation of compound words. Otherwords that use the affix cyto- include: cytopathic, cytopathogenic, cytosol, cytotaxonomy, endocytobiology
Examples of 'immunocytochemistry' in a sentence
immunocytochemistry
In addition, immunocytochemistry staining and flow cytometric analysis were performed to investigate the cell-surface markers.
Raheleh Farahzadi, Ezzatollah Fathi, Seyed Alireza Mesbah-Namin, Nosratollah Zarghami 2017, 'Zinc sulfate contributes to promote telomere length extension via increasing telomerasegene expression, telomerase activity and change in the TERT gene promoter CpG islandmethylation status of human adipose-derived mesenchymal stem cells', PLOS ONE10.1371/journal.pone.0188052. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We used immunocytochemistry, flow cytometry and immunoblotting techniques and surprisingly found no cross-species immunoreactivity.
Kristina Thamm, Sylvi Graupner, Carsten Werner, Wieland B. Huttner, Denis Corbeil 2016, 'Monoclonal Antibodies 13A4 and AC133 Do Not Recognize the Canine Ortholog of Mouseand Human Stem Cell Antigen Prominin-1 (CD133)', PLOS ONE10.1371/journal.pone.0164079. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Immunocytochemistry confirmed that both mutants are present on the cell membrane albeit at low levels.
Javier A. Tello, Claire L. Newton, Jerome Bouligand, Anne Guiochon-Mantel, RobertP. Millar, Jacques Young 2012, 'Congenital Hypogonadotropic Hypogonadism Due to GNRH Receptor Mutations in Three BrothersReveal Sites Affecting Conformation and Coupling', PLoS ONE10.1371/journal.pone.0038456. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Such differences were confirmed using immunocytochemistry and western blotting assays.
Silvia Berardis, Catherine Lombard, Jonathan Evraerts, Adil El Taghdouini, ValérieRosseels, Pau Sancho-Bru, Juan Jose Lozano, Leo van Grunsven, Etienne Sokal, MustaphaNajimi 2014, 'Gene Expression Profiling and Secretome Analysis Differentiate Adult-Derived HumanLiver Stem/Progenitor Cells and Human Hepatic Stellate Cells', PLoS ONE10.1371/journal.pone.0086137. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Both recombinant cell lines were characterised by fluorescence microscopy, flow cytometry and immunocytochemistry.
Saskia Willenbrock, Siegfried Wagner, Nicola Reimann-Berg, Mohammed Moulay, MarionHewicker-Trautwein, Ingo Nolte, Hugo Murua Escobar 2014, 'Generation and Characterisation of a Canine EGFP-HMGA2 Prostate Cancer In Vitro Model',PLoS ONE10.1371/journal.pone.0098788. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The isolated and cultured cells from chick embryos were identified by cellular morphology and immunocytochemistry.
Jianfeng Gao, Ding Zhang, Muhammad Shahzad, Kerong Zhang, Liru Zhao and Jiakui Li* 2013, 'Cultivation and Characterization of Pulmonary Microvascular Endothelial Cells fromChicken Embryos', Pakistan Veterinary Journalhttp://pvj.com.pk/pdf-files/33_3/300-303.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Retinal sections from various ages were prepared and compared histologically and by immunocytochemistry.
Leif E Johnson, Michael Larsen, Maria-Thereza Perez 2013, 'Retinal adaptation to changing glycemic levels in a rat model of type 2 diabetes.',PLoS ONEhttp://europepmc.org/articles/PMC3568153?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Co-immunoprecipitation, pull-down and immunocytochemistry experiments confirmed the interactions.
Carmen-Alexandra Tanase 2010, 'Histidine domain-protein tyrosine phosphatase interacts with Grb2 and GrpL.', PLoS ONEhttp://europepmc.org/articles/PMC3002266?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Immunocytochemistry labeling of neuron-specific tubulin confirmed the initiation of neural differentiation.
Ana M. Magariños, Sara Pedron, Marc Creixell, Murat Kilinc, Inna Tabansky, DonaldW. Pfaff, Brendan A. C. Harley, Brendan A. C. Harley 2018, 'The Feasibility of Encapsulated Embryonic Medullary Reticular Cells to Grow and DifferentiateInto Neurons in Functionalized Gelatin-Based Hydrogels', Frontiers in Materialshttps://www.frontiersin.org/article/10.3389/fmats.2018.00040/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)