Some strains adapted to this particular niche show distinct phenotypes, such as biofilm hyperproduction.
Cynthia Gagné-Thivierge, Irena Kukavica-Ibrulj, Geneviève Filion, Valérie Dekimpe,Sok Gheck E. Tan, Antony T. Vincent, Éric Déziel, Roger C. Levesque, Steve J. Charette 2018, 'A multi-host approach to identify a transposon mutant of Pseudomonas aeruginosa LESB58lacking full virulence', BMC Research Noteshttp://link.springer.com/article/10.1186/s13104-018-3308-7. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These abnormalities include the contractility and hyperproduction of inflammatory proteins.
Benjamin Kalbe, Jürgen Knobloch, Viola Maria Schulz, Christine Wecker, Marian Schlimm,Paul Scholz, Fabian Jansen, Erich Stoelben, Stathis Philippou, Erich Hecker, HermannLuebbert, Andrea Koch, Hanns Hatt, Sabrina Osterloh 2016, 'Olfactory receptors modulate physiological processes in human airway smooth musclecells', Frontiers in Physiologyhttp://journal.frontiersin.org/Journal/10.3389/fphys.2016.00339/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Again, eprosartan reduced this hyperproduction.
Marcial Martínez Silvestre 2005, 'The Effects of Eprosartan on Cytoplasmic Free Calcium Mobilisation, Platelet Activationand Microparticle Formation in Hypertension. Could they be Relevant to Stroke Prevention?',Journal of the Renin-Angiotensin-Aldosterone Systemhttps://doi.org/10.1177/14703203050060010101. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Hyperproduction of mucus was slightly reduced.
Chiaki Iwamura, Kenta Shinoda, Mineka Yoshimura, Yukiko Watanabe, Akio Obata, ToshinoriNakayama 2010, 'Naringenin Chalcone Suppresses Allergic Asthma by Inhibiting the Type-2 Function ofCD4 T Cells', Allergology Internationalhttp://www.sciencedirect.com/science/article/pii/S1323893015305773. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The components are considered to induce apoptosis-like programmed cell death via hyperproduction of reactive oxygen species.
Xia Da, Yayoi Nishiyama, Duerna Tie, Kyaw Zaw Hein, Osamu Yamamoto, Eishin Morita 2019, 'Antifungal activity and mechanism of action of Ou-gon (Scutellaria root extract) componentsagainst pathogenic fungi', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-019-38916-w. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)