[1940–45; hyper- + -phagia]This word is first recorded in the period 1940–45. Other words that entered Englishat around the same time include: Rh factor, blockbuster, debrief, redline, set-asidehyper- is a prefix appearing in loanwords from Greek, where it meant “over,” usually implyingexcess or exaggeration (hyperbole). On this model, hyper- is used, especially as opposed to hypo-, in the formation of compound words (hyperthyroid). Other words that use the affix hyper- include: hyperbaric, hypercharge, hyperkinesia, hyperopia, hyperparathyroidism
Examples of 'hyperphagia' in a sentence
hyperphagia
Impairments in brain insulin signaling causes dysregulation of feeding behaviors and, as a consequence, hyperphagia.
Olga I. Dadalko, Kevin Niswender, Aurelio Galli 2015, 'Impaired mTORC2 signaling in catecholaminergic neurons exaggerates high fat diet-inducedhyperphagia', Heliyonhttp://www.sciencedirect.com/science/article/pii/S2405844015302917. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Development of obesity was concomitant with hyperphagia, increased food efficiency, and decreased activity.
Géraldine M. Mang, Sylvain Pradervand, Ngoc-Hien Du, Alaaddin Bulak Arpat, FrédéricPreitner, Leonore Wigger, David Gatfield, Paul Franken 2015, 'A Neuron-Specific Deletion of the MicroRNA-Processing Enzyme DICER Induces Severebut Transient Obesity in Mice', PLOS ONE10.1371/journal.pone.0116760. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Hyperprolactinemia occurs during gestation and lactation with marked hyperphagia associated with leptin resistance.
Nadège Carré, Gili Solomon, Arieh Gertler, Nadine Binart 2014, 'Effects of high affinity leptin antagonist on prolactin receptor deficient male mouse.',PLoS ONEhttp://europepmc.org/articles/PMC3965386?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The brain's inability to control energy homeostasis underlies the pathology of hyperphagia and obesity.
Eun Roh, Min-Seon Kim 2016, 'Brain Regulation of Energy Metabolism', Endocrinology and Metabolismhttp://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-31-519.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, the hyperphagia did not lead to a higher growth rate or body fat percentage.
Binbin Zheng, Shuisheng Li, Yun Liu, Yu Li, Huapu Chen, Haipei Tang, Xiaochun Liu,Haoran Lin, Yong Zhang, Christopher H. K. Cheng 2017, 'Spexin Suppress Food Intake in Zebrafish: Evidence from Gene Knockout Study', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-017-15138-6. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Uncommon manifestations included hyperphagia, sudden death, and thermodysregulation.
ulie Martin-Grace, Giovanni Murialdo, Gianluca Tamagno 2015, 'Hypothalamic–Pituitary Alterations in Patients With Neurosarcoidosis', European Medical Journal Neurologyhttp://emjreviews.com/wp-content/uploads/Hypothalamic-Pituitary-ALterations-in-Patients-with-Neurosarcoidosis.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Two-thirds of participants experienced hyperphagia and half were not satiated after a meal.
Yvonne C Anderson, Lisa E Wynter, Michelle S Butler, Cameron C Grant, Joanna M Stewart,Tami L Cave, Cervantée E K Wild, José G B Derraik, Wayne S Cutfield, Paul L Hofman 2016, 'Dietary Intake and Eating Behaviours of Obese New Zealand Children and AdolescentsEnrolled in a Community-Based Intervention Programme.', PLoS ONEhttp://europepmc.org/articles/PMC5120841?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Monogenic leptin deficiency results in severe early onset obesity with hyperphagia.
Juraj Stanik, Jürgen Kratzsch, Kathrin Landgraf, Kathrin Scheuermann, Ulrike Spielau,Ruth Gausche, Daniela Gasperikova, Wieland Kiess, Antje Körner 2017, 'Concordance of bioactive vs. total immunoreactive serum leptin levels in childrenwith severe early onset obesity.', PLoS ONEhttp://europepmc.org/articles/PMC5441582?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Conversely, they cause behavioural changes, such as hyperphagia, that result in a positive energy balance.
Hiroyuki Iuchi, Masaya Sakamoto, Daisuke Matsutani, Hirofumi Suzuki, Yosuke Kayama,Norihiko Takeda, Susumu Minamisawa, Kazunori Utsunomiya 2017, 'Time-dependent effects of ipragliflozin on behaviour and energy homeostasis in normaland type 2 diabetic rats: continuous glucose telemetry analysis', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-017-12106-y. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)