释义 |
tumor necrosis factor in American English a protein produced by macrophages in response to bacterial infection: a form made by genetic engineering is used in the treatment of cancer tumor necrosis factor in American Englishnouna protein, produced in humans and other animals, that is destructive to cells showing abnormally rapid growth: identical with cachectin Abbreviation: TNF Examples of 'tumor necrosis factor' in a sentencetumor necrosis factor Intravitreal levels of tumor necrosis factor-alpha and tumor necrosis factor-beta were undetectable.These include tumor necrosis factor-α inhibitors and other biologicals.Tumor necrosis factor content increased for 50–60%.Maximum increase of tumor necrosis factor-α was detected in cases of mixed-infections.Specifically, antibodies to tumor necrosis factor alpha induce rapid mucosal healing.Further, interleukin-1β, interleukin-6, and tumor necrosis factor-α levels were reduced.Reports increased during 2004–2008, especially for patients treated with anti–tumor necrosis factor agents.Moreover, the upregulation of tumor necrosis factor-α was observed during pembrolizumab therapy.This typically requires immune suppression by steroids, thiopurines, methotrexate, or tumor necrosis factor inhibitors.The patient then received anti-tumor necrosis factor-α with good response. |