Phosphatidic acid phosphatases are involved in the biosynthesis of phospholipids and triacylglycerol, and also act as transcriptional regulators.
Anoop Narayana Pillai, Sushmita Shukla, Abdur Rahaman 2017, 'An evolutionarily conserved phosphatidate phosphatase maintains lipid droplet numberand endoplasmic reticulum morphology but not nuclear morphology', Biology Openhttp://bio.biologists.org/content/6/11/1629. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We found two species of monohexosylceramide and 33 phospholipid species, includingphosphatidylcholine, phosphatidylethanolamine, phosphatidic acid, phosphatidylserine,phosphatidylinositol, and phosphatidylglycerol.
Milene C Vallejo, Ernesto S Nakayasu, Larissa V G Longo, Luciane Ganiko, Felipe GLopes, Alisson L Matsuo, Igor C Almeida, Rosana Puccia 2012, 'Lipidomic analysis of extracellular vesicles from the pathogenic phase of Paracoccidioidesbrasiliensis.', PLoS ONEhttp://europepmc.org/articles/PMC3382159?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In addition, a decrease in phosphatidic acid, phosphatidylcholine, phosphatidylserine and phosphatidylethanolamine,and an increase in phosphatidylinositol were observed.
Zhong-peng Guo, Sakda Khoomrung, Jens Nielsen, Lisbeth Olsson 2018, 'Changes in lipid metabolism convey acid tolerance in Saccharomyces cerevisiae', Biotechnology for Biofuelshttp://link.springer.com/article/10.1186/s13068-018-1295-5. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The content of phospholipids in the oils, mainly phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and phosphatidicacids was 1.1%, 7.5% and 2.8% respectively.
Zlatanov, M., Vazvazova, P. 1999, 'Lipid composition of Evonimus japonicus L., Piracanttia coccinea L. and Amelanchiercannadensis L. seed oils', Grasas y Aceiteshttp://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/678/689. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We then determined the spatial and concentration-dependent distributions of 20 phosphatidylcholines, 6 phosphatidylethanolamines, and 4 phosphatidic acids.
Jaroslav Pól, Veronika Vidová, Tuulia Hyötyläinen, Michael Volný, Petr Novák, MartinStrohalm, Risto Kostiainen, Vladimír Havlíček, Susanne K Wiedmer, Juha M Holopainen 2011, 'Spatial distribution of glycerophospholipids in the ocular lens.', PLoS ONEhttp://europepmc.org/articles/PMC3084859?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Lipids with small headgroups, such as phosphatidic acid, are conical and impose negative curvature on a monolayer.
Takashi Hirama, Gregory D. Fairn 2018, 'Induction of spontaneous curvature and endocytosis: Unwanted consequences of cholesterolextraction using methyl-β-Cyclodextrin', Communicative & Integrative Biologyhttp://dx.doi.org/10.1080/19420889.2018.1444306. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)