a white crystalline powder, C19H22ClN5O, used in the treatment of major depression disorders
Word origin
[tr(i)- + azo- + (pyri)d(ine) + -one]-one is a suffix used in the names of ketones and analogous chemical compounds. Otherwords that use the affix -one include: lactone, quinone
Examples of 'trazodone' in a sentence
trazodone
Patients were randomly assigned to trazodone group and placebo group for 3 months.
Hong-ju ZHANG, Xiao-feng JIANG, Ming-ming MA, Jie-wen ZHANG 2013, 'A control study on treatment for benzodiazepine dependence with trazodone', Chinese Journal of Contemporary Neurology and Neurosurgeryhttp://www.cjcnn.org/index.php/cjcnn/article/view/724. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Although generally well tolerated, trazodone treatment can be associated with some complications.
Gustavo Santos, Ana Maria Moreira 2017, 'Distressing Visual Hallucinations after Treatment with Trazodone', Case Reports in Psychiatryhttp://dx.doi.org/10.1155/2017/6136914. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We describe a case of a 60-year-old man who received trazodone for primary insomnia.
Gustavo Santos, Ana Maria Moreira 2017, 'Distressing Visual Hallucinations after Treatment with Trazodone', Case Reports in Psychiatryhttp://dx.doi.org/10.1155/2017/6136914. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Sedative effect and use of trazodone, mirtazapine, doxepine, amitryptilin are described.
Dalva Poyares, Luciano Ribeiro Pinto Jr, Stella Tavares, Sergio Barros-Vieira 2005, 'Hipnoindutores e insônia Sleep promoters and insomnia', Revista Brasileira de Psiquiatriahttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462005000500002. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Trazodone was associated with a significantly increased risk of upper gastrointestinal bleed.
Carol Coupland, Trevor Hill, Richard Morriss, Michael Moore, Antony Arthur, JuliaHippisley-Cox 2018, 'Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohortstudy using a primary care database', BMC Medicinehttp://link.springer.com/article/10.1186/s12916-018-1022-x. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Given the widespread use of trazodone, clinicians should be aware of this possible side effect.
Gustavo Santos, Ana Maria Moreira 2017, 'Distressing Visual Hallucinations after Treatment with Trazodone', Case Reports in Psychiatryhttp://dx.doi.org/10.1155/2017/6136914. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The lower values were obtained in trazodone pre-treated animals.
Radivoj Jadrić, Emina Kiseljaković, Sabaheta Hasić, Mira Winterhalter-Jadrić 2007, 'ß-endorphins as Possible Markers for Therapeutic Drug Monitoring', Bosnian Journal of Basic Medical Scienceshttp://www.bjbms.org/ojs/index.php/bjbms/article/view/3081. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Our research aimed to develop a new method for the synthesis of trazodone and its derivatives.
Jolanta Jaśkowska, Przemysław Zaręba, Paweł Śliwa, Edyta Pindelska, Grzegorz Satała,Zbigniew Majka 2019, 'Microwave-Assisted Synthesis of Trazodone and Its Derivatives as New 5-HT1ALigands: Binding and Docking Studies', Moleculeshttps://www.mdpi.com/1420-3049/24/8/1609. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Moreover, cinnarizine and trazodone were proven to be good candidates as skin-whitening agents for treatment of skin hyperpigmentation.
Te-Sheng Chang, Victor Chia-Hsiang Lin 2011, 'Melanogenesis Inhibitory Activity of Two Generic Drugs: Cinnarizine and Trazodonein Mouse B16 Melanoma Cells', International Journal of Molecular Scienceshttp://www.mdpi.com/1422-0067/12/12/8787/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Fourteen patients received 3mg of melatonin and eighteen patients received 50mg of trazodone before sleep time.
Zahra Mirsepassi, Shima Saedi, Haleh Behpournia, Behrang Shadloo, Valentin Artounian,Seyyed Taha Yahyavi, Maryam Tabatabaei, Mehdi Soleimani, Sana Khajehpour, PadidehGhaeli 2018, 'Comparing Effects of Melatonin versus Trazodone on Sleep Quality in Major DepressedPatients Receiving Sertraline', Journal of Pharmaceutical Carehttp://jpc.tums.ac.ir/index.php/jpc/article/view/157. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)