Production in algal chloroplasts avoids these issues because chloroplasts can fold complex eukaryotic proteins and do not glycosylate proteins.
James A Gregory, Fengwu Li, Lauren M Tomosada, Chesa J Cox, Aaron B Topol, JosephM Vinetz, Stephen Mayfield 2012, 'Algae-produced Pfs25 elicits antibodies that inhibit malaria transmission.', PLoS ONEhttp://europepmc.org/articles/PMC3353897?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)