a drug that is used to ease congestion in the nasal passages and treat low blood pressure
phenylephrine, a decongestant that doctors commonly prescribe
phenylephrine in American English
(ˌfenlˈefrin, -rɪn, ˌfin-)
noun
Pharmacology
an alpha-adrenergic stimulant, C19H13NO2, used chiefly as a nasal decongestant
Word origin
[1945–50; phenyl + (epin)ephrine]This word is first recorded in the period 1945–50. Other words that entered Englishat around the same time include: RNA, ergative, on-line, regression analysis, taxi squad
Examples of 'phenylephrine' in a sentence
phenylephrine
Topical phenylephrine solutions are widely used in eye procedures to promote pupil dilation without cycloplegia.
Ashraf A Abdelhalim, Mohamed Mostafa, Ahmed Abdulmomen, Essam A Othman 2012, 'Severe hypertension and pulmonary edema associated with systemic absorption of topicalphenylephrine in a child during retinal surgery', Saudi Journal of Anaesthesiahttp://www.saudija.org/article.asp?issn=1658-354X;year=2012;volume=6;issue=3;spage=285;epage=288;aulast=Abdelhalim. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
There was no need for phenylephrine treatment in the preeclamptic group.
Atanas Sivevski, E Ivanov, Dafina Кaradjova, Maja Slaninka-Miceska, Igor Kikerkov 2019, 'Spinal-Induced Hypotension in Preeclamptic and Healthy Parturients Undergoing CesareanSection', Open Access Macedonian Journal of Medical Scienceshttps://www.id-press.eu/mjms/article/view/2455. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Phenylephrine, epinephrine, vasopressin and terlipressin are considered second-line agents.
Tomer Avni, Adi Lador, Shaul Lev, Leonard Leibovici, Mical Paul, Alon Grossman 2015, 'Vasopressors for the Treatment of Septic Shock: Systematic Review and Meta-Analysis.',PLoS ONEhttp://europepmc.org/articles/PMC4523170?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Cd induced hypertension and impaired vascular responses to phenylephrine, acetylcholine and sodium nitroprusside.
Upa Kukongviriyapan, Patchareewan Pannangpetch, Veerapol Kukongviriyapan, Wanida Donpunha,Kwanjit Sompamit, Praphassorn Surawattanawan 2014, 'Curcumin Protects against Cadmium-Induced Vascular Dysfunction, Hypertension and TissueCadmium Accumulation in Mice', Nutrientshttp://www.mdpi.com/2072-6643/6/3/1194. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Furthermore, the relationships between metabolic and microvascular oscillators were examined during phenylephrine-induced vasoconstriction.
Salvatore Smirni, Alison D. McNeilly, Michael P. MacDonald, Rory J. McCrimmon, FaiselKhan 2019, 'In-vivo correlations between skin metabolic oscillations and vasomotion in wild-typemice and in a model of oxidative stress', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-018-36970-4. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The tendency for peripheral accumulation of fluid was pronounced, in particular when phenylephrine was given.
Yuhong Li, Zheng Xiaozhu, Ru Guomei, Ding Qiannan, Robert G Hahn 2017, 'Effects of vasoactive drugs on crystalloid fluid kinetics in septic sheep.', PLoS ONEhttp://europepmc.org/articles/PMC5322902?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Moreover, vascular reactivity of the isolated aortic rings to phenylephrine and acetylcholine was tested.
Nevein Hendawy, Amany Helmy, Hala Salah Abdel Kawy, Ghada Karouk Mohamed, Ahmed ElSayed Badawy, Hoda Sallam 2012, 'Differential Effects of Ivabradine and Metoprolol on Cardiovascular Remodeling andMyocardial Infarction Induced by Isoprenaline in Chronic N-nitro-L-arginine MethylEster (L-NAME) Treated Rats', Egyptian Journal of Basic and Clinical Pharmacologyhttp://www.kenzpub.com/journals/ejbcp/2012/101333/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Fundus examination was done after dilating the pupils with 0.5% tropicamide and 2.5% phenylephrine eyedrops.
Vidya Hegde, Soni Soman, Rashmi Jain, Anupama Bappal, Rashmi Shambhu 2018, 'Retinal hemorrhages in term newborns – Our experience at tertiary centre', Journal of Clinical Ophthalmology and Researchhttp://www.jcor.in/article.asp?issn=2320-3897;year=2018;volume=6;issue=1;spage=8;epage=11;aulast=Hegde. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Endothelial damage abolished the increased reactivity to phenylephrine.
Núbia Belem Lemos, Jhuli Keli Angeli, Thaís de Oliveira Faria, Rogério Faustino RibeiroJunior, Dalton Valentim Vassallo, Alessandra Simão Padilha, Ivanita Stefanon 2012, 'Low mercury concentration produces vasoconstriction, decreases nitric oxide bioavailabilityand increases oxidative stress in rat conductance artery.', PLoS ONEhttp://europepmc.org/articles/PMC3492199?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)