the mainland of Spanish America, esp the N coast of South America from the Isthmus of Panama to the mouth of the Orinoco River, Venezuela
2.
the Caribbean Sea, the S part of which in colonial times was the route of Spanish treasure galleons and the haunt of pirates
Spanish Main in American English
Obsolete
1.
the coastal region of the Americas along the Caribbean Sea; esp., the N coast of South America between the Isthmus ofPanama & the mouth of the Orinoco
an earlier usage
2.
later, the Caribbean Sea itself, or that part of it adjacent to the N coast of South America, traveled in the 16th-18th cent. by Spanish merchant ships, which were often harassed by pirates
Examples of 'Spanish Main' in a sentence
Spanish Main
He would have left the place as fast as he could, as so many of the other guests were doing, and set sail for the Spanish Main.