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单词 gentisic acid
释义

gentisic acid in American English

(dʒɛnˈtɪsɪk)
a crystalline, water-soluble acid, C6H3(OH)2COOH, whose sodium salt has been used in medicine as an analgesic
Word origin
< gentisin, pigment derived from gentian root < ModL Gentiana, gentian + trypsin + -ic

gentisic acid in American English

(dʒenˈtɪsɪk, -ˈtɪz-)
noun
Pharmacology
a crystalline, water-soluble compound, C7H6O4, used chiefly in the form of its sodium salt as an analgesic and diaphoretic
Word origin
[1875–80; genti(an) + -s- connective + -ic]This word is first recorded in the period 1875–80. Other words that entered Englishat around the same time include: cross-fertilization, knockabout, massage, neoclassic, slime mold-ic is a suffix forming adjectives from other parts of speech, occurring originally inGreek and Latin loanwords (metallic; poetic; archaic; public) and, on this model, used as an adjective-forming suffix with the particular senses“having some characteristics of” (opposed to the simple attributive use of the basenoun) (balletic; sophomoric); “in the style of” (Byronic; Miltonic); “pertaining to a family of peoples or languages” (Finnic; Semitic; Turkic)

Examples of 'gentisic acid' in a sentence
gentisic acid

Here, we examined whether gentisic acid prevents the development of heart failure.
Simei Sun, Hae Jin Kee, Yuhee Ryu, Sin Young Choi, Gwi Ran Kim, Hyung-Seok Kim, Seung-JungKee, Myung Ho Jeong 2019, 'Gentisic acid prevents the transition from pressure overload-induced cardiac hypertrophyto heart failure', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-019-39423-8. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Among the natural phenolic compounds, gentisic acid was the most active.
Milagros Rico, Idayra Sánchez, Cristina Trujillo, Norma Pérez 2013, 'Screening of the antioxidant properties of crude extracts of six selected plant speciesfrom the Canary Islands (Spain)', Journal of Applied Botany and Food Qualityhttps://ojs.openagrar.de/index.php/JABFQ/article/view/2506. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Major phenolic acids were gentisic acid, homogentisic acid, and small amounts of caffeicacid.
Vamanu Emanuel, Pelinescu Diana, Avram Ionela 2018, 'Antioxidative Effects of Phenolic Compounds of Mushroom Mycelia in Simulated Regionsof the Human Colon, In Vitro Study', Polish Journal of Food and Nutrition Scienceshttp://www.degruyter.com/view/j/pjfns.2018.68.issue-1/pjfns-2017-0010/pjfns-2017-0010.xml?format=INT. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Gentisic acid, epicatechin and quercitrin were the most prominent phenolic compounds of the flowers.
Milagros Rico, Ana S. Ramírez, Orestes Vega-Orellana, Miguel Suárez de Tangil, AroaLópez 2013, 'Phenolic Constituents, Antioxidant and Preliminary Antimycoplasmic Activities of LeafSkin and Flowers of Aloe vera (L.) Burm. f. (syn. A. barbadensis Mill.) from the CanaryIslands (Spain)', Moleculeshttp://www.mdpi.com/1420-3049/18/5/4942. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The gentisic acid molecule shows whole-molecule disorder over two sets of sites in a 0.809 (2):0.191 (2) ratio.
Elizabeth M. Horstman, Jeffery A. Bertke, Toby J. Woods, Paul J. A. Kenis 2016, 'Crystal structure of a 2:1 piroxicam–gentisic acid co-crystal featuring neutral andzwitterionic piroxicam molecules', Acta Crystallographica Section E: Crystallographic Communicationshttp://scripts.iucr.org/cgi-bin/paper?S2056989016017321. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
To stabilize and ensure a good quality of the labeled radiopharmaceuticals, ascorbic or gentisic acid were added.
NADEZDA VUKICEVIC, JURIJ VUCINA 2001, 'Stabilization of Tc-99m radiopharmaceuticals by chemical additives (NOTE)', Journal of the Serbian Chemical Societyhttp://www.shd.org.yu/HtDocs/SHD/Vol66/No9/V66-No9-03.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
An endogenous siderophore composed of gentisic acid (2,5-dihydroxybenzoic acid) substituents was proposed to mediate cellular efflux.
Colin Correnti, Vera Richardson, Allyson K Sia, Ashok D Bandaranayake, Mario Ruiz,Yohan Suryo Rahmanto, Žaklina Kovačević, Matthew C Clifton, Margaret A Holmes, BrettK Kaiser, Jonathan Barasch, Kenneth N Raymond, Des R Richardson, Roland K Strong 2012, 'Siderocalin/Lcn2/NGAL/24p3 does not drive apoptosis through gentisic acid mediatediron withdrawal in hematopoietic cell lines.', PLoS ONEhttp://europepmc.org/articles/PMC3424236?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Using this pathway, nitrate-reducing bacteria decompose resorcinol, a-resorcylate, 3-hydroxybenzoate, gentisic acid and possibly hydroquinonein hydroxylation and decarboxylation reactions.
Verkholiak N.S., Peretyatko T.B. 2018, 'Utilization of aromatic compounds by bacteria. II. Flexibility of aromatic xenobiotics', Біологічні студіїhttp://publications.lnu.edu.ua/journals/index.php/biology/article/view/841. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
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更新时间：2025/3/22 8:31:10