Two groups of 50 periodontally healthy adolescents were enrolled in the longitudinal study.
Daniel H Fine, Kenneth Markowitz, Karen Fairlie, Debbie Tischio-Bereski, Javier Ferrandiz,Dipti Godboley, David Furgang, John Gunsolley, Al Best 2014, 'Macrophage inflammatory protein-1α shows predictive value as a risk marker for subjectsand sites vulnerable to bone loss in a longitudinal model of aggressive periodontitis.',PLoS ONEhttp://europepmc.org/articles/PMC4047026?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Periodontally compromised abutments complicate the treatment plan of distal extension removable partial dentures.
Allahyar Geramy, Mehdi Adibrad, Mahasti Sahabi 2010, 'The effects of splinting periodontally compromised removable partial denture abutmentson bone stresses: a three-dimensional finite element study', Journal of Dental Scienceshttp://www.sciencedirect.com/science/article/pii/S1991790210600013. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Forty-two periodontally healthy subjects were divided according to peri-implant condition:healthy and peri-implantitis groups.
Jaime S. Marques Filho, Jorge Gobara, Gustavo Vargas da Silva Salomao, Laura M. Sumita,Jamil A. Shibli, Renato G. Viana, Humberto O. Schwartz Filho, Claudio Sergio Pannuti,Paulo Henrique Braz-Silva, Debora Pallos 2018, 'Cytokine Levels and Human Herpesviruses in Saliva from Clinical Periodontal HealthySubjects with Peri-Implantitis: A Case-Control Study', Mediators of Inflammationhttp://dx.doi.org/10.1155/2018/6020625. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Conversely, pro-inflammatory molecules released by periodontally-diseased tissues may enterthe circulation to induce insulin resistance.
Waleed F Janem, Frank A Scannapieco, Amarpeet Sabharwal, Maria Tsompana, Harvey ABerman, Elaine M Haase, Jeffrey C Miecznikowski, Lucy D Mastrandrea 2017, 'Salivary inflammatory markers and microbiome in normoglycemic lean and obese childrencompared to obese children with type 2 diabetes.', PLoS ONEhttp://europepmc.org/articles/PMC5333807?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We included 30 periodontally healthy patients as a control.
Pallavi S. Ghodpage, Rajashri A. Kolte, Abhay P. Kolte, Madhur Gupta 2014, 'Influence of phase I periodontal therapy on levels of matrix metalloproteinase 1 andtissue inhibitor of metalloproteinase 1', Saudi Dental Journalhttp://www.sciencedirect.com/science/article/pii/S101390521400056X. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Putative oral pathogens are commonly found in periodontally diseased individuals.
André Göhler, Adrian Hetzer, Birte Holtfreter, Marie Henrike Geisel, Carsten OliverSchmidt, Ivo Steinmetz, Thomas Kocher 2014, 'Quantitative molecular detection of putative periodontal pathogens in clinically healthyand periodontally diseased subjects.', PLoS ONEhttp://europepmc.org/articles/PMC4100758?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Seventy-five periodontally healthy controls and 75 subjects affected by chronic periodontitis were recruited.
N. Arias-Bujanda, A. Regueira-Iglesias, M. Alonso-Sampedro, M. M. González-Peteiro,A. Mira, C. Balsa-Castro, I. Tomás 2018, 'Cytokine Thresholds in Gingival Crevicular Fluid with Potential Diagnosis of ChronicPeriodontitis Differentiating by Smoking Status', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-018-35920-4. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)