the fluid filling the space between the membranous and bony labyrinths of the internal ear
perilymph in American English
(ˈpɛrəˌlɪmf)
noun
the fluid that surrounds the membranous labyrinth of the inner ear
see also endolymph
perilymph in American English
(ˈperɪˌlɪmf)
noun
Anatomy
the fluid between the bony and membranous labyrinths of the ear
Derived forms
perilymphatic
adjective
Word origin
[1830–40; peri- + lymph]This word is first recorded in the period 1830–40. Other words that entered Englishat around the same time include: format, isomerism, paraffin, showcase, stroboscopeperi- is a prefix meaning “about” or “around” (perimeter, periscope), “enclosing” or “surrounding” (pericardium), and “near” (perigee, perihelion), appearing in loanwords from Greek (peripeteia). On this model, peri- is used in the formation of compound words (perimorph)
Examples of 'perilymph' in a sentence
perilymph
Originally the actuator was intended for direct perilymph stimulation after stapedotomyusing a piston prosthesis.
Martin Grossöhmichen, Rolf Salcher, Hans-Heinrich Kreipe, Thomas Lenarz, Hannes Maier 2015, 'The Codacs™ Direct Acoustic Cochlear Implant Actuator: Exploring Alternative StimulationSites and Their Stimulation Efficiency', PLOS ONE10.1371/journal.pone.0119601. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Perilymph specimens were collected at different times.
Pedro Marques, Maoli Duan, Nicolas Perez-Fernandez, Jorge Spratley 2018, 'Gentamicin delivery to the inner ear: Does endolymphatic hydrops matter?', PLoS ONEhttp://europepmc.org/articles/PMC6237362?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The decrease in perilymph wave impedance likely accounts for the auditory changes.
Bu-Sheng Tong, Zi-Yu He, Chen-Ru Ding, Juan-Mei Yang, Jing Wang, Zhao Han, Yi-Bo Huang,Na Gao, Xian-Hao Jia, Fang-Lu Chi, Dong-Dong Ren 2018, 'Mechanisms of Hearing Loss in a Guinea Pig Model of Superior Semicircular Canal Dehiscence',Neural Plasticityhttp://dx.doi.org/10.1155/2018/1258341. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Analyzed by mass spectrometry were 41 perilymph samples despite three patients undergoing bilateral cochlear implantation.
Ines de Vries, Heike Schmitt, Heike Schmitt, Thomas Lenarz, Thomas Lenarz, Nils Prenzler,Sameer Alvi, Hinrich Staecker, Martin Durisin, Athanasia Warnecke, Athanasia Warnecke 2019, 'Detection of BDNF-Related Proteins in Human Perilymph in Patients With Hearing Loss',Frontiers in Neurosciencehttps://www.frontiersin.org/article/10.3389/fnins.2019.00214/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The mean concentration was 49.7±9.4 of 10 perilymph samples.
Tetsuo Ikezono, Tomohiro Matsumura, Han Matsuda, Satomi Shikaze, Shiho Saitoh, SusumuShindo, Setsuo Hasegawa, Seung Ha Oh, Yoshiaki Hagiwara, Yasuo Ogawa, Hiroshi Ogawa,Hiroaki Sato, Tetsuya Tono, Ryuichiro Araki, Yukihide Maeda, Shin-Ichi Usami, YasuhiroKase 2018, 'The diagnostic performance of a novel ELISA for human CTP (Cochlin-tomoprotein) todetect perilymph leakage.', PLoS ONEhttp://europepmc.org/articles/PMC5788340?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Descriptions of “spontanenous” perilymph fistulas with no trauma history followed.
Jeremy Hornibrook 2012, 'A Balance Test for Chronic Perilymph Fistula', International Journal of Otolaryngologyhttp://dx.doi.org/10.1155/2012/163691. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The measurements, however, involved perforating the cochlear bony wall and, in some cases, sampling perilymph.
Ildar I. Sadreev, George W. S. Burwood, Samuel M. Flaherty, Jongrae Kim, Ian J. Russell,Timur I. Abdullin, Andrei N. Lukashkin, Andrei N. Lukashkin 2019, 'Drug Diffusion Along an Intact Mammalian Cochlea', Frontiers in Cellular Neurosciencehttps://www.frontiersin.org/article/10.3389/fncel.2019.00161/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In addition, functional analysis showed that numerous processes were significantly increased in the perilymph.
Jesper Edvardsson Rasmussen, Göran Laurell, Helge Rask-Andersen, Jonas Bergquist,Per Olof Eriksson 2018, 'The proteome of perilymph in patients with vestibular schwannoma. A possibility toidentify biomarkers for tumor associated hearing loss?', PLoS ONEhttp://europepmc.org/articles/PMC5983529?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
For such an approach, perilymph concentrations achieved and the distribution in the ear over time have not previously been documented.
Alec Salt, Jared Hartsock, Ruth Gill, Daniel Smyth, Jonathon Kirk, Kristien Verhoeven 2017, 'Perilymph pharmacokinetics of marker applied through a cochlear implant in guineapigs', PLOS ONE10.1371/journal.pone.0183374. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In pathway analysis perilymph had highly enriched functions, particularly in terms of increased immune and metabolic processes.
Jesper Edvardsson Rasmussen, Göran Laurell, Helge Rask-Andersen, Jonas Bergquist,Per Olof Eriksson 2018, 'The proteome of perilymph in patients with vestibular schwannoma. A possibility toidentify biomarkers for tumor associated hearing loss?', PLoS ONEhttp://europepmc.org/articles/PMC5983529?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)