The two geminal bromine-atom substituents point to opposite sides of the aromatic ring system.
Sin-Kai Fang, Hong-Yi Lin, Kew-Yu Chen 2012, '1,2-Bis(dibromomethyl)benzene', Acta Crystallographica Section Ehttp://scripts.iucr.org/cgi-bin/paper?S1600536811050616. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This review recapitulates all available literature dealing with the synthesis and reactivity of geminal organic di- and triazides.
Andreas P. Häring, Stefan F. Kirsch 2015, 'Synthesis and Chemistry of Organic Geminal Di- and Triazides', Moleculeshttp://www.mdpi.com/1420-3049/20/11/19675. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The structural conformation also demonstrated by coupling constants derived from dihedral angles between vicinal and geminal protons.
N. N. Pesyan, S. Noori, S. Poorhassan, E. Şahin 2014, 'New spiro (thio) barbiturates based on cyclohexanone and bicyclo [3.1.1]heptan-6-oneby nonconcerted [1+5] cycloaddition reaction and their conformational structures',Bulletin of the Chemical Society of Ethiopiahttp://www.ajol.info/index.php/bcse/article/view/108087. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Our group has previously reported a new stereoselective route to access derivatives modified at the geminal dimethyl moiety.
Jinming Guan, Matthew Hachey, Lekha Puri, Vanessa Howieson, Kevin J. Saliba, KarineAuclair 2016, 'A cross-metathesis approach to novel pantothenamide derivatives', Beilstein Journal of Organic Chemistryhttps://doi.org/10.3762/bjoc.12.95. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)