a collection of all the messenger RNA in a particular cell
Examples of 'transcriptome' in a sentence
transcriptome
Compared to in vitro conditions, the in vivo transcriptome was dramatically altered within 30 minutes.
Donald O Chaffin, Destry Taylor, Shawn J Skerrett, Craig E Rubens 2012, 'Changes in the Staphylococcus aureus transcriptome during early adaptation to thelung.', PLoS ONEhttp://europepmc.org/articles/PMC3410880?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A transcriptome captures a snapshot in time of the total transcripts present in a cell.
Rohan Lowe, Neil Shirley, Mark Bleackley, Stephen Dolan, Thomas Shafee 2017, 'Transcriptomics technologies.', PLoS Computational Biologyhttp://europepmc.org/articles/PMC5436640?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The findings improve our understanding of the complexity of porcine transcriptome.
Congying Chen, Rongxing Wei, Ruimin Qiao, Jun Ren, Hui Yang, Chenlong Liu, LushengHuang 2012, 'A genome-wide investigation of expression characteristics of natural antisense transcriptsin liver and muscle samples of pigs.', PLoS ONEhttp://europepmc.org/articles/PMC3527515?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Results revealed a differential expression of apoptosis related genes in the transcriptome.
Karori S. Mbuthia, Paul O. Mireji, Raphael M. Ngure, Francesca Stomeo, Martina Kyallo,Chalo Muoki, Francis N. Wachira 2017, 'Tea (Camellia sinensis) infusions ameliorate cancer in 4TI metastatic breast cancermodel', BMC Complementary and Alternative Medicinehttp://link.springer.com/article/10.1186/s12906-017-1683-6. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Therefore, researchers have tried to develop tools to analyze transcriptome data withpathway based interpretation.
Inyoung Kim, Saemi Choi, Sun Kim 2018, 'BRCA-Pathway: a structural integration and visualization system of TCGA breast cancerdata on KEGG pathways', BMC Bioinformaticshttp://link.springer.com/article/10.1186/s12859-018-2016-6. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Integrative analysis of transcriptome and proteome data identified ten enthesis biomarkers and six tendon biomarkers.
Lara A Kuntz, Leone Rossetti, Elena Kunold, Andreas Schmitt, Ruediger von Eisenhart-Rothe,Andreas R Bausch, Rainer H Burgkart 2018, 'Biomarkers for tissue engineering of the tendon-bone interface.', PLoS ONEhttp://europepmc.org/articles/PMC5751986?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Integration with transcriptome dynamics also uncovers regulatory hubs at the transcriptional level.
Hiroko eKozuka-Hata, Shinya eTasaki, Masaaki eOyama 2012, 'Phosphoproteomics-based systems analysis of signal transduction networks', Frontiers in Physiologyhttp://journal.frontiersin.org/Journal/10.3389/fphys.2011.00113/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We developed a marker gene-based approach for scoring single-cell transcriptome quality post-hoc.
Shreejoy J. Tripathy, Shreejoy J. Tripathy, Lilah Toker, Lilah Toker, Claire Bomkamp,B. Ogan Mancarci, B. Ogan Mancarci, Manuel Belmadani, Manuel Belmadani, Paul Pavlidis,Paul Pavlidis 2018, 'Assessing Transcriptome Quality in Patch-Seq Datasets', Frontiers in Molecular Neurosciencehttps://www.frontiersin.org/article/10.3389/fnmol.2018.00363/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Bayesian modeling was used to generate the temporal profiles of the transcriptome during fracture healing.
Manish Bais, Jody McLean, Paola Sebastiani, Megan Young, Nathan Wigner, Temple Smith,Darrell N Kotton, Thomas A Einhorn, Louis C Gerstenfeld 2009, 'Transcriptional analysis of fracture healing and the induction of embryonic stem cell-relatedgenes.', PLoS ONEhttp://europepmc.org/articles/PMC2673045?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
To overcome these limitations, transcriptome data were generated for three representative corallimorpharians.
Mei Fang Lin, Wen Hwa Chou, Marcelo V. Kitahara, Chao Lun Allen Chen, David John Miller,Sylvain Forêt 2016, 'Corallimorpharians are not “naked corals”: insights into relationships between Scleractiniaand Corallimorpharia from phylogenomic analyses', PeerJhttps://peerj.com/articles/2463.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)