a process of metabolism whereby the metabolized drug or chemical is more toxic than the parent drug or chemical
Examples of 'toxication' in a sentence
toxication
Examining the toxic response in the acute toxicity test, there was no sign of toxication.
Ki-Rok, Kwon, A-La, Cho, Sun-Gu, Lee 2003, 'The Study on Acute and Subacute Toxicity and Anti-Cancer Effects of cultivated wildginseng Herbal acupuncture', Journal of Pharmacopuncturehttp://dx.doi.org/10.3831/KPI.2003.6.2.007. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
It reduces heavy metal toxication by chelating.
Armağan Yürük , Aylin Ayaz 2014, 'The Health Effects of Alpha Lipoic Acid', Hacettepe Üniversitesi Sağlık Bilimleri Fakültesi Dergisihttp://dergipark.gov.tr/download/article-file/88798. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Like other types of toxications, intravenous toxication has pulmonary involvement, however in this case we had multiple organ involvement.
Hadi Hamishehkar, Hassan Soleimanpour, Ata Mahmoodpoor 2012, 'Multi Organ Failure Following Intravenous Gasoline for Suicide: A Case Report', Acta Medica Iranicahttp://acta.tums.ac.ir/index.php/acta/article/view/4605/4284. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Donor cells co-produce immunity proteins and shuttle them into their own periplasm to prevent accidental toxication by siblings.
Juliane Benz, Jochen Reinstein, Anton Meinhart 2013, 'Structural Insights into the Effector - Immunity System Tae4/Tai4 from Salmonellatyphimurium.', PLoS ONEhttp://europepmc.org/articles/PMC3695027?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The resulting multiscale model was used to investigate hyperuricemia therapy, ammonia detoxification and paracetamol-induced toxication at a systems level.
Markus Krauss, Stephan Schaller, Steffen Borchers, Rolf Findeisen, Jörg Lippert, LarsKuepfer 2012, 'Integrating cellular metabolism into a multiscale whole-body model.', PLoS Computational Biologyhttp://europepmc.org/articles/PMC3486908?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)