an antidepressant drug that acts by preventing the re-uptake after release of serotonin in the brain, thereby prolonging its action: used for treating depression, obsessive-compulsive disorders, and panic disorder. Formula: C19H20FNO3
Examples of 'paroxetine' in a sentence
paroxetine
She recovered in a few days after re-administration of paroxetine.
Horst J. Koch 2015, 'REPEATED CONFUSIONAL STATES FOLLOWING DISCONTINUATION OF PROXETINE IN A 51-YEAR-OLDWOMEN SUFFERING FROM PSYCHOTIC DEPRESSION', Acta Medica Medianaehttp://publisher.medfak.ni.ac.rs/2015-html/2015%203-broj/Celi%20radovi%20pdf%202015-3/Horst%20J.%20Koch.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Oral administration of paroxetine, but not its subcutaneous administration, dose-dependently caused emesis in both animals.
Yukiko Mine, Seiko Oku, Naoyuki Yoshida 2013, 'Anti-emetic Effect of Mosapride Citrate Hydrate, a 5-HT4 Receptor Agonist, on SelectiveSerotonin Reuptake Inhibitors (SSRIs)-Induced Emesis in Experimental Animals', Journal of Pharmacological Scienceshttp://www.sciencedirect.com/science/article/pii/S1347861319304049. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
138 cases enrolled were randomly assigned to an electro-acupuncture group and a paroxetine group.
Yu Wang, You-ping Hu, Wen-chun Wang, Ri-zhao Pang, An-ren Zhang 2012, 'Clinical Studies on Treatment of Earthquake-Caused Posttraumatic Stress Disorder UsingElectroacupuncture', Evidence-Based Complementary and Alternative Medicinehttp://dx.doi.org/10.1155/2012/431279. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Low-dose risperidone appears to be tolerated equally well as paroxetine.
Galynker Igor I, Cohen Lisa J, Steele Annie, Yard Samantha, Prosser James M 2009, 'A comparison of low-dose risperidone to paroxetine in the treatment of panic attacks:a randomized, single-blind study', BMC Psychiatryhttp://www.biomedcentral.com/1471-244X/9/25. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Paroxetine was started at 5 mg in the evening, with the intention of titrating up.
Roni Y. Kraut 2017, 'Treatment of pruritus in a palliative care patient with low-dose paroxetine: a casereport', Journal of Medical Case Reportshttp://link.springer.com/article/10.1186/s13256-017-1437-6. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The selective serotonin reuptake inhibitor paroxetine (3 mg/kg), was used as a positive control.
Marcel P. Rangel, João Carlos P. de Mello, Elisabeth A. Audi 2013, 'Evaluation of neurotransmitters involved in the anxiolytic and panicolytic effectof the aqueous fraction of Paullinia cupana (guaraná) in elevated T maze', Revista Brasileira de Farmacognosiahttp://www.sciencedirect.com/science/article/pii/S0102695X13700474. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Overall change in placebo-treated individuals replicated 79% of the magnitude of paroxetine response.
Michael A Sugarman, Amy M Loree, Boris B Baltes, Emily R Grekin, Irving Kirsch 2014, 'The efficacy of paroxetine and placebo in treating anxiety and depression: a meta-analysisof change on the Hamilton Rating Scales.', PLoS ONEhttp://europepmc.org/articles/PMC4146610?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The patients' paroxetine plasma concentrations at week 6 were measured using high-performance liquid chromatography.
Tetsu Tomita, Norio Yasui-Furukori, Taku Nakagami, Shoko Tsuchimine, Masamichi Ishioka,Ayako Kaneda, Norio Sugawara, Sunao Kaneko 2014, 'The influence of 5-HTTLPR genotype on the association between the plasma concentrationand therapeutic effect of paroxetine in patients with major depressive disorder.',PLoS ONEhttp://europepmc.org/articles/PMC4032230?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)