释义 |
fibrate in British English (ˈfaɪbreɪt) nounany of a class of drugs used to lower fat levels in the body Examples of 'fibrate' in a sentencefibrate Statin and fibrate combination increases the risk of rhabdomyolysis possibly by pharmacodynamic interactions.Combined statin-fibrate therapy increases the risk of rhabdomyolysis, especially in elderly and diabetic patients.However, increased physical activity can enhance the statin and fibrate-associated myopathy.Of this group, 213 (19.4%) were statin users and 4 (0.4%) were fibrate users.Users of pravastatin, fluvastatin, ezetimib and fibrate more seldom reach treatment goals.Similarly, fibrate therapy comparing to placebo had no effect on the incidence of fatal stroke.Therefore, these patients may benefit from fibrates or combined statin/fibrate treatment.Of these, 8,545 (95%) received statin alone and 437 (5%) received fibrate/statin combination.The patient maintains mild hypertriglyceridemia without rebound after single plasmapheresis and maintenance fibrate medication so far. |