to produce offspring through sexual relations outside a particular family or tribe
2.
to breed (animals that are not closely related) or (of such animals) to be bred
Derived forms
outbreeding (ˌoutˈbreeding)
noun
Examples of 'outbred' in a sentence
outbred
We show that this protocol detects previously well-established genetic differences between outbred fruit fly populations.
Kennedy Matsagas, David B Lim, Marc Horwitz, Cristina L Rizza, Laurence D Mueller,Bryant Villeponteau, Michael R Rose 2009, 'Long-term functional side-effects of stimulants and sedatives in Drosophila melanogaster.',PLoS ONEhttp://europepmc.org/articles/PMC2719805?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We developed a standardized protocol to create, replicate and maintain isofemale lines and outbred populations.
Vítor G. Faria, Élio Sucena, Élio Sucena 2017, 'From Nature to the Lab: Establishing Drosophila Resources for Evolutionary Genetics',Frontiers in Ecology and Evolutionhttp://journal.frontiersin.org/article/10.3389/fevo.2017.00061/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Still, embryos are born at predicted mendelian ratios on an outbred background.
Ellen Dees, Paul M. Miller, Katherine L. Moynihan, Ryan D. Pooley, R. Pierre Hunt,Cristi L. Galindo, Jeffrey N. Rottman, David M. Bader 2012, 'Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilatedcardiomyopathy', Disease Models & Mechanismshttp://dmm.biologists.org/content/5/4/468. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These data provide a baseline expectation for gene variation in an outbred population.
Elise Ruark, Márton Münz, Anthony Renwick, Matthew Clarke, Emma Ramsay, Sandra Hanks,Shazia Mahamdallie, Anna Elliott, Sheila Seal, Ann Strydom, Lunter Gerton, NazneenRahman 2015, 'The ICR1000 UK exome series: a resource of gene variation in an outbred population[version 1; referees: 2 approved]', F1000Researchhttp://f1000research.com/articles/4-883/v1. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In outbred strains, individual variability may affect some behavioral measures.
João Victor Nicodemos Pildervasser, Karina Possa Abrahao, Maria Lucia Oliveira Souza-Formigoni 2014, 'Distinct behavioral phenotypes in ethanol-induced place preference are associatedwith different extinction and reinstatement but not behavioral sensitization responses',Frontiers in Behavioral Neurosciencehttp://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00267/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Furthermore, the mutation was significantly associated with ear size across the experimental cross and diverse outbred populations.
Jun Ren, Yanyu Duan, Ruimin Qiao, Fei Yao, Zhiyan Zhang, Bin Yang, Yuanmei Guo, ShijunXiao, Rongxin Wei, Zixuan Ouyang, Nengshui Ding, Huashui Ai, Lusheng Huang 2011, 'A missense mutation in PPARD causes a major QTL effect on ear size in pigs.', PLoS Geneticshttp://europepmc.org/articles/PMC3088719?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We therefore investigated whether epigenomic changes could be detected after a non-drastic change in the environment of an outbred organism.
Angelika G Börsch-Haubold, Inka Montero, Kathryn Konrad, Bernhard Haubold 2014, 'Genome-wide quantitative analysis of histone H3 lysine 4 trimethylation in wild housemouse liver: environmental change causes epigenetic plasticity.', PLoS ONEhttp://europepmc.org/articles/PMC4029994?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Our results suggest that in outbred populations multi-locus diversity might be important for coping with parasitism.
María José Ruiz-López, Ryan J Monello, Matthew E Gompper, Lori S Eggert 2012, 'The effect and relative importance of neutral genetic diversity for predicting parasitismvaries across parasite taxa.', PLoS ONEhttp://europepmc.org/articles/PMC3458861?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Our results also highlight the importance of correcting for population structure in whole-genome association studies in the outbred stock.
Anatole Ghazalpour, Sudheer Doss, Hyun Kang, Charles Farber, Ping-Zi Wen, Alec Brozell,Ruth Castellanos, Eleazar Eskin, Desmond J Smith, Thomas A Drake, Aldons J Lusis 2008, 'High-resolution mapping of gene expression using association in an outbred mouse stock.',PLoS Geneticshttp://europepmc.org/articles/PMC2483929?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)