an antimicrobial substance, C8H10N2S, used against susceptible Mycobacterium tuberculosis in combination with other drugs in the treatment of any active form of tuberculosis
Word origin
[1960–65; e(thyl) + thion(ic) + amide]This word is first recorded in the period 1960–65. Other words that entered Englishat around the same time include: disco, parvovirus, power play, proxemics, zip code
Examples of 'ethionamide' in a sentence
ethionamide
Toxic symptoms appeared earlier with higher doses of ethionamide.
Gupta D 1977, 'Acceptability of thioamides I. ethionamide', Journal of Postgraduate Medicinehttp://www.jpgmonline.com/article.asp?issn=0022-3859;year=1977;volume=23;issue=4;spage=175;epage=180;aulast=Gupta. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Resistance to isoniazid and ethionamide was found to be high (31 and 38%, respectively).
Azger Dusthackeer, Gomathi Sekar, Shambhavi Chidambaram, Vanaja Kumar, Pranav Mehta,Soumya Swaminathan 2015, 'Drug resistance among extrapulmonary TB patients: Six years experience from a supranationalreference laboratory', Indian Journal of Medical Researchhttp://www.ijmr.org.in/article.asp?issn=0971-5916;year=2015;volume=142;issue=5;spage=568;epage=574;aulast=Dusthackeer. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Resistance to ethionamide and amikacin was 2.3% and 1.6%, respectively.
Syed Mohammad Asad Zaidi, Abdul Haseeb, Shifa Salman Habib, Amyn Malik, Saira Khowaja,Nausheen SaifUllah, Nadeem Rizvi 2017, 'Emergence of fluoroquinolone resistance among drug resistant tuberculosis patientsat a tertiary care facility in Karachi, Pakistan', BMC Research Noteshttp://link.springer.com/article/10.1186/s13104-017-2633-6. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Adverse events were most commonly attributed to cycloserine, ethionamide and p-aminosalicylic acid.
Helen S Cox, Stobdan Kalon, Sholpan Allamuratova, Vinciane Sizaire, Zinaida N Tigay,Sabine Rüsch-Gerdes, Hamraev A Karimovich, Yared Kebede, Clair Mills 2007, 'Multidrug-resistant tuberculosis treatment outcomes in Karakalpakstan, Uzbekistan:treatment complexity and XDR-TB among treatment failures.', PLoS ONEhttp://europepmc.org/articles/PMC2040509?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A standardized regimen of kanamycin, moxifloxacin, ethionamide, terizidone, and pyrazinamide was used accordingto national guidelines.
Kathryn Schnippel, Rebecca H. Berhanu, Andrew Black, Cynthia Firnhaber, Norah Maitisa,Denise Evans, Edina Sinanovic 2016, 'Severe adverse events during second-line tuberculosis treatment in the context ofhigh HIV Co-infection in South Africa: a retrospective cohort study', BMC Infectious Diseaseshttp://link.springer.com/article/10.1186/s12879-016-1933-0. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In vitro resistance to ethionamide emerged earlier and was the most frequent followed by resistance to cycloserine and kanamycin.
Isabel N. De Kantor, Lucía Barrera 2007, 'Susceptibility tests to second line drugs and re-treatment of tuberculosis: RevisitingEarly Experiences Las pruebas de sensibilidad a drogas de segunda línea y el re-tratamientode la tuberculosis: Visión retrospectiva de tres estudios', Medicina (Buenos Aires)http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0025-76802007000300002. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Age, chronicity of illness and extent of disease did not exhibit any influence on ethionamide acceptability.
Gupta D 1977, 'Acceptability of thioamides I. ethionamide', Journal of Postgraduate Medicinehttp://www.jpgmonline.com/article.asp?issn=0022-3859;year=1977;volume=23;issue=4;spage=175;epage=180;aulast=Gupta. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Pretomanid treatments generated a unique distinctive metabolite profile when compared to ampicillin, ethambutol, ethionamide, isoniazid, kanamycin, linezolid, rifampicinand streptomycin.
Rafael Baptista, David M. Fazakerley, Manfred Beckmann, Les Baillie, Luis A. J. Mur 2018, 'Untargeted metabolomics reveals a new mode of action of pretomanid (PA-824)', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-018-23110-1. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)