| 释义 | 
		Example sentencessignificant challenge  The country is facing significant environmental challenges.Smoking remains one of our most significant public health challenges.This was not just a significant challenge but also a decidedly risky career change.  Seebig challengeSeesignificant gapCOBUILD Collocationssignificant challenge  accept a challenge  address a challenge  aerial challenge  big challenge  confront a challenge  constant challenge  court challenge  daunting challenge  different challenge  difficult challenge  embrace a challenge  enjoy a challenge  enormous challenge  exciting challenge  face a challenge  formidable challenge  fresh challenge  gruelling challenge  highlight the challenge  intellectual challenge  issue a challenge  launch a challenge  like a challenge  main challenge  major challenge  massive challenge  meet a challenge  new challenge  overcome a challenge  prove a challenge  real challenge  represent a challenge  serious challenge  significant challenge  tackle a challenge  technical challenge  throw down a challenge  unique challenge  |