the hydrogen bonding that occurs between complementary nitrogenous bases in the two polynucleotide chains of a DNA molecule
Examples of 'base pairing' in a sentence
base pairing
In both the compounds base pairing also occurs.
Muthiah Packianathan, Balasubramani Kasthuri, Lynch Daniel E 2007, 'R22(8) motifs in Aminopyrimidine sulfonate/carboxylate interactions:Crystal structures of pyrimethaminium benzenesulfonate monohydrate (2:2:1) and 2-amino-4,6-dimethylpyrimidiniumsulfosalicylate dihydrate (4:2:2)', Chemistry Central Journalhttp://journal.chemistrycentral.com/content/1/1/28. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This process yields updated estimates of base pairing probability.
Sharma Gaurav, Harmanci Arif O, Mathews David H 2011, 'TurboFold: Iterative probabilistic estimation of secondary structures for multipleRNA sequences', BMC Bioinformaticshttp://www.biomedcentral.com/1471-2105/12/108. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The specificity of these interactions derives from the stability of inter-molecular base pairing.
Stadler Peter F, Flamm Christoph, Mückstein Ulrike, Tafer Hakim, Bernhart StephanH, Hofacker Ivo L 2006, 'Partition function and base pairing probabilities of RNA heterodimers', Algorithms for Molecular Biologyhttp://www.almob.org/content/1/1/3. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In stems, several compensatory mutations were detected that maintain base pairing.
Venanzetti Federica, Johnsen Arild, Martinsen Lene, Bachmann Lutz 2010, 'Phylogenetic footprinting of non-coding RNA: hammerhead ribozyme sequences in a satelliteDNA family of Dolichopoda cave crickets (Orthoptera, Rhaphidophoridae)',BMC Evolutionary Biologyhttp://www.biomedcentral.com/1471-2148/10/3. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Pentose diphosphates comprise the backbone monomers of pentopyranose nucleic acids, some of the strongest base pairing systems so far discovered.
Harold S. Bernhardt 2019, 'Making Molecules with Clay: Layered Double Hydroxides, Pentopyranose Nucleic Acidsand the Origin of Life', Lifehttps://www.mdpi.com/2075-1729/9/1/19. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
To achieve multi-point recognition, we designed the uracil-appended version of this probe to include complementary base-pairing interactions.
Márton Bojtár, Péter Zoltán Janzsó-Berend, Dávid Mester, Dóra Hessz, Mihály Kállay,Miklós Kubinyi, István Bitter 2018, 'An uracil-linked hydroxyflavone probe for the recognition of ATP', Beilstein Journal of Organic Chemistryhttps://doi.org/10.3762/bjoc.14.63. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In mutants with repaired base pairing either in stem 1 or in stem 2 full translational activity was restored.
Moes Lorin, Wirth Manfred 2007, 'The internal initiation of translation in bovine viral diarrhea virus RNA dependson the presence of an RNA pseudoknot upstream of the initiation codon', Virology Journalhttp://www.virologyj.com/content/4/1/124. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, the reasons underlying its effects, especially those not directly explained by the altered base pairing ability, are poorly understood.
Joanna J. Hoppins, David R. Gruber, Heather L. Miears, Alexey S. Kiryutin, RustemD. Kasymov, Darya V. Petrova, Anton V. Endutkin, Alexander V. Popov, Alexandra V.Yurkovskaya, Stanislav O. Fedechkin, Jacob A. Brockerman, Dmitry O. Zharkov, SergeL. Smirnov 2016, '8-Oxoguanine Affects DNA Backbone Conformation in the EcoRI Recognition Site and InhibitsIts Cleavage by the Enzyme', PLOS ONE10.1371/journal.pone.0164424. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)