a smooth sac within the cell, formed by or fused with coated vesicles that shed their clathrin, in which ligands are separated from their receptors and from which the receptors are returned to the cell surface
Word origin
[endo- + -some3]-some is a combining form meaning “body,” used in the formation of compound words. Otherwords that use the affix -some include: microsome, monosome, nucleosome, schistosome, trypanosome
Examples of 'endosome' in a sentence
endosome
Localization studies further validated that this conjugate escaped the endosome.
Manoj Saxena, Yamixa Delgado, Rohit Kumar Sharma, Shweta Sharma, Solimar Liz PonceDe León Guzmán, Arthur D. Tinoco, Kai Griebenow 2018, 'Inducing cell death in vitro in cancer cells by targeted delivery of cytochrome cvia a transferrin conjugate', PLOS ONE10.1371/journal.pone.0195542. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We further showed that vanadate inhibits endosome fusion.
Mojca Zelnikar, Mojca Benčina, Roman Jerala, Mateja Manček-Keber 2014, 'Vanadate from air pollutant inhibits hrs-dependent endosome fusion and augments responsivenessto toll-like receptors.', PLoS ONEhttp://europepmc.org/articles/PMC4047122?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Ecotropic murine leukemia virus entry requires cathepsin proteases activated by the endosome acidification.
Yoshinao Kubo, Hideki Hayashi, Toshifumi Matsuyama, Hironori Sato, Naoki Yamamoto 2012, 'Retrovirus Entry by Endocytosis and Cathepsin Proteases', Advances in Virologyhttp://dx.doi.org/10.1155/2012/640894. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Many animal retroviruses enter host cells through endosomes and require endosome acidification.
Yoshinao Kubo, Hideki Hayashi, Toshifumi Matsuyama, Hironori Sato, Naoki Yamamoto 2012, 'Retrovirus Entry by Endocytosis and Cathepsin Proteases', Advances in Virologyhttp://dx.doi.org/10.1155/2012/640894. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
At rest, endosome-like organelles were detected in the region of the cuticular plate.
Dirk Kamin, Natalia H Revelo, Silvio O Rizzoli 2014, 'FM dye photo-oxidation as a tool for monitoring membrane recycling in inner hair cells.',PLoS ONEhttp://europepmc.org/articles/PMC3914975?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These dynamic events might drive functional diversification of the signaling endosome.
Kelly Barford, Austin Keeler, Lloyd McMahon, Kathryn McDaniel, Chan Choo Yap, ChristopherD. Deppmann, Bettina Winckler 2018, 'Transcytosis of TrkA leads to diversification of dendritic signaling endosomes', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-018-23036-8. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Our results show that the endosome-associated movement of virus particles fluctuates from fast to slow.
Elina Mäntylä, Jenu V. Chacko, Vesa Aho, Colin R. Parrish, Victor Shahin, MichaelKann, Michelle A. Digman, Enrico Gratton, Maija Vihinen-Ranta 2018, 'Viral highway to nucleus exposed by image correlation analyses', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-018-19582-w. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Of particular interest was the enrichment for genes involved in endosome recycling.
Michael G. Connor, Amanda R. Pulsifer, Donghoon Chung, Eric C. Rouchka, Brian K. Ceresa,Matthew B. Lawrenz, Michele S. Swanson 2018, 'Yersinia pestis Targets the Host Endosome Recycling Pathway during the Biogenesisof the Yersinia-Containing Vacuole To Avoid Killing by Macrophages', mBiohttp://mbio.asm.org/cgi/content/full/9/1/e01800-17. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Our data suggest a mechanistic link between endosome positioning and postsynaptic structure and composition.
Marta Esteves da Silva, Max Adrian, Philipp Schätzle, Joanna Lipka, Takuya Watanabe,Sukhee Cho, Kensuke Futai, Corette J. Wierenga, Lukas C. Kapitein, Casper C. Hoogenraad 2015, 'Positioning of AMPA Receptor-Containing Endosomes Regulates Synapse Architecture',Cell Reportshttp://www.sciencedirect.com/science/article/pii/S2211124715011043. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)