They are expressed in the same synaptic vesicles which participate in the exo-endocytotic cycle.
Giorgia Fattorini, Giorgia Fattorini, Chiara Ciriachi, Fiorenzo Conti, Fiorenzo Conti,Fiorenzo Conti 2017, 'Few, Activity-Dependent, and Ubiquitous VGLUT1/VGAT Terminals in Rat and Mouse Brain',Frontiers in Cellular Neurosciencehttp://journal.frontiersin.org/article/10.3389/fncel.2017.00229/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Cultured podocytes exhibited endocytotic uptake of albumin.
Caroline Rauch, Elisabeth Feifel, Georg Kern, Cormac Murphy, Florian Meier, WaltherParson, Mario Beilmann, Paul Jennings, Gerhard Gstraunthaler, Anja Wilmes 2018, 'Differentiation of human iPSCs into functional podocytes.', PLoS ONEhttp://europepmc.org/articles/PMC6141081?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Like monomers a small fraction of the oligomers initially enter cells by a non-endocytotic mechanism.
Saurabh Trikha, Aleksandar M Jeremic 2013, 'Distinct internalization pathways of human amylin monomers and its cytotoxic oligomersin pancreatic cells.', PLoS ONEhttp://europepmc.org/articles/PMC3760900?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The viral particles entering through the endocytotic pathway were destroyed within 1-2 days.
Dongyang Yu, Weifeng Wang, Alyson Yoder, Mark Spear, Yuntao Wu 2009, 'The HIV envelope but not VSV glycoprotein is capable of mediating HIV latent infectionof resting CD4 T cells.', PLoS Pathogenshttp://europepmc.org/articles/PMC2760144?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Cationic functionalization of vesicles promoted endocytotic uptake.
Oliver Bixner, Noga Gal, Christoph Zaba, Andrea Scheberl, Erik Reimhult 2017, 'Fluorescent Magnetopolymersomes: A Theranostic Platform to Track Intracellular Delivery',Materialshttps://www.mdpi.com/1996-1944/10/11/1303. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Most likely, the internalization occurs by a specific endocytotic pathway via acidified endosomes.
Lydia Dmochewitz, Christina Förtsch, Christian Zwerger, Martin Vaeth, Edward Felder,Markus Huber-Lang, Holger Barth 2013, 'A recombinant fusion toxin based on enzymatic inactive C3bot1 selectively targetsmacrophages.', PLoS ONEhttp://europepmc.org/articles/PMC3549961?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We assume that toxin uptake might additionally occur through alternative receptor structures and/or other associated endocytotic pathways.
Alexandra Olling, Sebastian Goy, Florian Hoffmann, Helma Tatge, Ingo Just, Ralf Gerhard 2011, 'The Repetitive Oligopeptide Sequences Modulate Cytopathic Potency but Are Not Crucialfor Cellular Uptake of Clostridium difficile Toxin A', PLoS ONE10.1371/journal.pone.0017623. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Dynamin 1-3 isoforms are known to be involved in endocytotic processes occurring duringsynaptic transmission.
Mauro Fà, Agnieszka Staniszewski, Faisal Saeed, Yitshak I Francis, Ottavio Arancio 2014, 'Dynamin 1 is required for memory formation.', PLoS ONEhttp://europepmc.org/articles/PMC3958425?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
To assess endocytotic activity, the uptake of fluorescently labeled latex beads was analyzed by fluorescence microscopy.
Xiaorong Xin, Bin Fan, Josef Flammer, Neil R Miller, Gregor P Jaggi, Hanspeter E Killer,Peter Meyer, Albert Neutzner 2011, 'Meningothelial cells react to elevated pressure and oxidative stress.', PLoS ONEhttp://europepmc.org/articles/PMC3096659?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Two types of vesicles exist in the somatic cortex: globular endocytotic vesicles and flattened exocytotic vesicles.
Li Can, Jin Xiao, Li Ming, Wang Guitang, Zou Hong, Li Wenxiang, Wu Shangong 2017, 'Light and transmission electron microscopy of Cepedea longa (Opalinidae) from Fejervaryalimnocharis', Parasitehttps://doi.org/10.1051/parasite/2017006. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)