(in philosophy) that which is not the 'self', that is the external world
2. immunology
matter which is foreign to a particular body, thus triggering an immune response when it enters the body
adjective
3. immunology
of or pertaining to what is foreign to the body
nonself in American English
(nɑnˈself)
noun
Immunology
any antigen-bearing foreign material that enters the body and normally stimulates an attack by the body's immune system (distinguished from self)
Word origin
[1870–75; non- + self]
Examples of 'nonself' in a sentence
nonself
It proposes that tolerance breaks down in the presence of nonself antigens.
Bruno Filipe Faria, Patricia Mostardinha, Fernao Vistulo de Abreu 2017, 'Can the Immune System Perform a t-Test?', PLOS ONE10.1371/journal.pone.0169464. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The self-nonself discrimination hypothesis remains a landmark concept in immunology.
Bruno Filipe Faria, Patricia Mostardinha, Fernao Vistulo de Abreu 2017, 'Can the Immune System Perform a t-Test?', PLoS ONEhttp://europepmc.org/articles/PMC5207702?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Then we derive a fixed point theorem for nonself set-valued contractions which are metrically inward.
O'Regan D, Amini-Harandi A 2010, 'Fixed Point Theorems for Set-Valued Contraction Type Maps in Metric Spaces', Fixed Point Theory and Applicationshttp://www.fixedpointtheoryandapplications.com/content/2010/390183. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Many biological species distinguish self from nonself by using different mechanisms.
Pengbo Cao, Xueming Wei, Ram Prasad Awal, Rolf Müller, Daniel Wall 2019, 'A Highly Polymorphic Receptor Governs Many Distinct Self-Recognition Types withinthe Myxococcales Order', mBiohttps://doi.org/10.1128/mBio.02751-18. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
To improve nonself space coverage rate, the immune detectors were encoded to hyperellipsoids.
Tianliang Lu, Lu Zhang, Yixian Fu 2018, 'A Novel Immune-Inspired Shellcode Detection Algorithm Based on Hyperellipsoid Detectors',Security and Communication Networkshttp://dx.doi.org/10.1155/2018/2063089. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The adaptive immune system reacts against pathogenic nonself, whereas it normally remains tolerant to self.
Sahamoddin eKhailaie, Fariba eBahrami, Mahyar eJanahmadi, Pedro eMilanez-Almeida,Jochen eHuehn, Michael eMeyer-Hermann, Michael eMeyer-Hermann 2013, 'A mathematical model of immune activation with a unified self-nonself concept', Frontiers in Immunologyhttp://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00474/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
As an application, we derive a coincidence point theorem for nonself-condensing set-valued maps.
A. Amini-Harandi, A. P. Farajzadeh, D. O'Regan, R. P. Agarwal 2009, 'Coincidence Point, Best Approximation, and Best Proximity Theorems for CondensingSet-Valued Maps in Hyperconvex Metric Spaces', Fixed Point Theory and Applicationshttp://dx.doi.org/10.1155/2008/543154. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Sponge grafting experiments simulate the effects of natural self or nonself contact under laboratory conditions.
Laura F. Grice, Bernard M. Degnan 2017, 'Transcriptomic Profiling of the Allorecognition Response to Grafting in the DemospongeAmphimedon queenslandica', Marine Drugshttp://www.mdpi.com/1660-3397/15/5/136. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This immunological civil war abrogates the self-nonself distinction.
Robert Root-Bernstein, Jacob Couturier 2006, 'Antigenic Complementarity in the Origins of Autoimmunity: A General Theory IllustratedWith a Case Study of Idiopathic Thrombocytopenia Purpura', Clinical and Developmental Immunologyhttp://dx.doi.org/10.1080/17402520600578731. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
An equilibrium problem and a strictly pseudocontractive nonself-mapping are investigated.
Yan Hao, Sun Young Cho 2012, 'Some Results on Strictly Pseudocontractive Nonself-Mappings and Equilibrium Problemsin Hilbert Spaces', Abstract and Applied Analysishttp://dx.doi.org/10.1155/2012/543040. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)