(ˌsɛrətəˈnɜːdʒɪk) or serotoninergic (ˌsɛrəˌtəʊnɪˈnɜːdʒɪk)
adjective
physiology
(of a nerve ending) activating or activated by serotonin
serotonergic in American English
(ˈserətnˈɜːrdʒɪk)
adjective
containing or activated by serotonin
Word origin
[1965–70; seroton(in) + -ergic]This word is first recorded in the period 1965–70. Other words that entered Englishat around the same time include: T cell, hired gun, isometric exercise, no-fault, overdub
Examples of 'serotonergic' in a sentence
serotonergic
In contrast, there was greater variation in the patterns of serotonergic neurons.
Sternberg Paul W, Ochoa Stacy, Stone Allison, Srinivasan Jagan, Rivard Laura, LoerCurtis M 2010, 'A comparison of experience-dependent locomotory behaviors and biogenic amine neuronsin nematode relatives of Caenorhabditis elegans', BMC Neurosciencehttp://www.biomedcentral.com/1471-2202/11/22. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Polymorphisms in genes concerned with serotonergic neurotransmission are associated with both behaviourand musical aptitude.
Andrew P Morley, Madan Narayanan, Rebecca Mines, Ashraf Molokhia, Sebastian Baxter,Gavin Craig, Cathryn M Lewis, Ian Craig 2012, 'AVPR1A and SLC6A4 polymorphisms in choral singers and non-musicians: a gene associationstudy.', PLoS ONEhttp://europepmc.org/articles/PMC3285181?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Serotonergic and dopaminergic systems are closely related.
E. Zoons, J. Booij, J. D. Speelman, Y. E. M. Dreissen, M. Smit, M. A. J. Tijssen 2017, 'Lower serotonin transporter binding in patients with cervical dystonia is associatedwith psychiatric symptoms', EJNMMI Researchhttp://link.springer.com/article/10.1186/s13550-017-0338-4. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Tonic spiking of serotonergic neurons establishes serotonin levels in the brain.
Boris Mlinar, Alberto Montalbano, Lukasz Piszczek, Cornelius Gross, Renato Corradetti 2016, 'Firing properties of genetically identified dorsal raphe serotonergic neurons in brainslices.', Frontiers in Cellular Neurosciencehttp://journal.frontiersin.org/Journal/10.3389/fncel.2016.00195/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Altered serotonergic neurotransmission may represent a crucial pathophysiological mechanism mediating stress-induced cardiac disturbances.
Luca Carnevali, Francesca Mastorci, Enrica Audero, Gallia Graiani, Stefano Rossi,Emilio Macchi, Sergio Callegari, Alessandro Bartolomucci, Eugene Nalivaiko, FedericoQuaini, Cornelius Gross, Andrea Sgoifo 2012, 'Stress-induced susceptibility to sudden cardiac death in mice with altered serotoninhomeostasis.', PLoS ONEhttp://europepmc.org/articles/PMC3399824?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We then discuss the cell-class specific effects of serotonergic centrifugal neurons on olfactory processing.
Kristyn M. Lizbinski, Andrew M. Dacks 2018, 'Intrinsic and Extrinsic Neuromodulation of Olfactory Processing', Frontiers in Cellular Neurosciencehttp://journal.frontiersin.org/article/10.3389/fncel.2017.00424/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Imaging the serotonergic system could improve diagnosis and therapy of multiple canine behavioural disorders.
Nick Van Laeken, Olivia Taylor, Ingeborgh Polis, Sara Neyt, Ken Kersemans, Andre Dobbeleir,Jimmy Saunders, Ingeborg Goethals, Kathelijne Peremans, Filip De Vos 2016, 'In Vivo Evaluation of Blood Based and Reference Tissue Based PET Quantifications of[11C]DASB in the Canine Brain.', PLoS ONEhttp://europepmc.org/articles/PMC4747581?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Genome-wide association studies also revealed genetic associations between the serotonergic system and obesity.
Chang-Myung Oh, Sangkyu Park, Hail Kim 2016, 'Serotonin as a New Therapeutic Target for Diabetes Mellitus and Obesity', Diabetes & Metabolism Journalhttps://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-40-89.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The ascending serotonergic projections are derived mainly from mesencephalic raphe nuclei.
G. R. Hassanzadeh G. Behzadi 2007, 'PROJECTIONS OF DORSAL AND MEDIAN RAPHE NUCLEI TO DORSAL AND VENTRAL STRIATUM', Acta Medica Iranicahttp://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5126.pdf&manuscript_id=5126. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)