a cancerous tumour that has spread from the site of original growth to a secondary site
Examples of 'disseminated cancer' in a sentence
disseminated cancer
The patient died 2 months later, with disseminated cancer.
Raja B. Hisham, Hashim Thuaibah, Yunus A. Gul 2006, 'Mucinous Adenocarcinoma of the Rectum with Breast and Ocular Metastases', Asian Journal of Surgeryhttp://www.sciencedirect.com/science/article/pii/S1015958409601159. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In order to spawn macroscopic metastases, disseminated cancer cells would seem to require self-renewal capability.
Mei-Hua Xu, Xuan Gao, Dan Luo, Xiang-Dong Zhou, Wei Xiong, Guo-Xiang Liu 2014, 'EMT and acquisition of stem cell-like properties are involved in spontaneous formationof tumorigenic hybrids between lung cancer and bone marrow-derived mesenchymal stemcells.', PLoS ONEhttp://europepmc.org/articles/PMC3916343?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Oncolytic viruses would ideally be of use for systemic therapy to treat disseminated cancer.
Tien V. Nguyen, Mary E. Barry, Mallory A. Turner, Catherine M. Crosby, Miguel A. Trujillo,John C. Morris, Michael A. Barry 2017, 'Comparison of Liver Detargeting Strategies for Systemic Therapy with Oncolytic AdenovirusSerotype 5', Biomedicineshttps://www.mdpi.com/2227-9059/5/3/46. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Patients with synchronous cancers have better prognosis than those with single disseminated cancer.
Sylwia Dębska-Szmich, Urszula Czernek, Magdalena Krakowska, Marta Frąckowiak, AgnieszkaZięba, Rafał Czyżykowski, Dominika Kulejewska, Piotr Potemski 2014, 'Synchronous primary ovarian and endometrial cancers: a series of cases and a reviewof literature', Menopause Reviewhttp://www.termedia.pl/Synchronous-primary-ovarian-and-endometrial-cancers-a-series-of-cases-and-a-review-of-literature,4,22414,1,1.html. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Tumor cells can persist undetectably for an extended period of time in primary tumors and in disseminated cancer cells.
Purvi ePatel, Emily eChen 2012, 'Cancer Stem Cells, Tumor Dormancy, And Metastasis', Frontiers in Endocrinologyhttp://journal.frontiersin.org/Journal/10.3389/fendo.2012.00125/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This paper discusses the main tools for detecting disseminated cancer cells currently available, their limitations, and clinical relevance.
Laurence Bockstaele, Sophie Tsepelidis, Julie Dechene, Yvon Englert, Isabelle Demeestere 2012, 'Safety of Ovarian Tissue Autotransplantation for Cancer Patients', Obstetrics and Gynecology Internationalhttp://dx.doi.org/10.1155/2012/495142. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)