partly synthetic and partly natural in composition
2.
produced from a natural substance by synthetic processes
semisynthetic in American English
(ˌsemisɪnˈθetɪk, ˌsemai-)
adjective
Chemistry
derived synthetically from one or more substances of natural origin
Word origin
[1935–40; semi- + synthetic]This word is first recorded in the period 1935–40. Other words that entered Englishat around the same time include: blitz, hard core, roadblock, unit trust, walk-throughsemi- is a combining form borrowed from Latin, meaning “half,” freely prefixed to Englishwords of any origin, now sometimes with the senses “partially,” “incompletely,” “somewhat”.Other words that use the affix semi- include: semiautomatic, semidetached, semimonthly, semisophisticated
Examples of 'semisynthetic' in a sentence
semisynthetic
The semisynthetic approach utilized was generally based on polysaccharide-controlled hydrolysis followed by reductive amination.
Juliana C. Cunico Dallagnol, Alexandre Orsato, Diogo R. B. Ducatti, Miguel D. Noseda,Maria Eugênia R. Duarte, Alan G. Gonçalves 2017, 'Aqueous semisynthesis of C-glycoside glycamines from agarose', Beilstein Journal of Organic Chemistryhttps://doi.org/10.3762/bjoc.13.121. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This work provides new precursor compounds for the semisynthetic modification of ramoplanin.
Jungang Han, Junsheng Chen, Lei Shao, Junliang Zhang, Xiaojing Dong, Pengyu Liu, DaijieChen 2016, 'Production of the Ramoplanin Activity Analogue by Double Gene Inactivation.', PLoS ONEhttp://europepmc.org/articles/PMC4858212?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Sealants and adhesives can be natural/biological, synthetic and semisynthetic.
Milenkovic B, Dimic Janjic S, Popevic S 2018, 'Review of lung sealant technologies for lung volume reduction in pulmonary disease',Medical Devices : Evidence and Researchhttps://www.dovepress.com/review-of-lung-sealant-technologies-for-lung-volume-reduction-in-pulmo-peer-reviewed-article-MDER. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Semisynthetic penicillins and macrolides were used most often.
Małgorzata Pietrzykowska, Katarzyna Nowicka-Sauer, Piotr Gutknecht, Janusz Siebert 2016, 'Incidence of respiratory tract infections and antibiotic use in primary health care',Family Medicine & Primary Care Reviewhttps://www.termedia.pl/Incidence-of-respiratory-tract-infections-and-antibiotic-use-in-primary-health-care,95,28458,1,1.html. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
All the semisynthetic derivatives were studied for their inhibitory potential against both acetylcholinesterase and butyrylcholinesterase.
Eliška Kohelová, Rozálie Peřinová, Negar Maafi, Jan Korábečný, Daniela Hulcová, JanaMaříková, Tomáš Kučera, Loreto Martínez González, Martina Hrabinova, Katarina Vorčáková,Lucie Nováková, Angela De Simone, Radim Havelek, Lucie Cahlíková 2019, 'Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-TargetDirected Ligands for Alzheimer's Disease', Moleculeshttps://www.mdpi.com/1420-3049/24/7/1307. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Semisynthetic beta-lactam antibiotics are among the most used pharmaceuticals.
Giovanilton Ferreira da Silva, José Sílvio Veras Albuquerque, Caroliny Gomes de Oliveira,Ricardo Emilio Ferreira Quevedo Nogueira, Andrea Lopes de Oliveira Ferreira 2009, 'The Kinetics of Ampicillin Release from Hydroxyapatite for Bones Regeneration', International Journal of Chemical Engineeringhttp://dx.doi.org/10.1155/2009/273808. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Antimicrobial substances may be synthetic, semisynthetic, or of natural origin (i.e., from plants and animals).
Gudepalya Renukaiah Rudramurthy, Mallappa Kumara Swamy, Uma Rani Sinniah, Ali Ghasemzadeh 2016, 'Nanoparticles: Alternatives Against Drug-Resistant Pathogenic Microbes', Moleculeshttp://www.mdpi.com/1420-3049/21/7/836. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
To overcome this problem, new semisynthetic aminoglycosides were developed in the 70s.
Maria S. Ramirez, Marcelo E. Tolmasky 2017, 'Amikacin: Uses, Resistance, and Prospects for Inhibition', Moleculeshttps://www.mdpi.com/1420-3049/22/12/2267. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Minocycline, a semisynthetic tetracycline-derived antibiotic, has been shown to exert anti-apoptotic, anti-inflammatory, and antioxidant effects.
Seyda Cankaya, Baris Cankaya, Ulkan Kilic, Ertugrul Kilic, Burak Yulug 2019, 'The therapeutic role of minocycline in Parkinson's disease', Drugs in Contexthttps://www.drugsincontext.com/the-therapeutic-role-of-minocycline-in-parkinsons-disease. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The second generation of semisynthetic tetracyclines, such as minocycline and doxycycline, with improved antimicrobial potency, were introduced during the 1960s.
Hrvoje Petković, Tadeja Lukežič, Jagoda Šušković 2017, 'Biosynthesis of Oxytetracycline by Streptomyces rimosus: Past, Present and FutureDirections in the Development of Tetracycline Antibiotics', Food Technology and Biotechnologyhttp://hrcak.srce.hr/file/262735. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)