Melanoma develops from neuroectodermal cells known as melanocytes.
Hanna H. Drobek, Beata S. Bergler-Czop, Bartosz Miziołek 2017, 'From chemotherapy to oncoviruses – modern methods of treatment in metastatic melanoma',Przegląd Dermatologicznyhttps://www.termedia.pl/From-chemotherapy-to-oncoviruses-modern-methods-of-treatment-in-metastatic-melanoma,56,30571,1,1.html. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Postoperative course was uneventful and postoperative histopathological examination revealed primitive neuroectodermal tumor.
Bashar Abuzayed, Wiam Khreisat, William Maaiah, Saoud Agailat 2014, 'Supratentorial primitive neuroectodermal tumor presenting with intracranial hemorrhagein adult', Journal of Neurosciences in Rural Practicehttp://www.ruralneuropractice.com/article.asp?issn=0976-3147;year=2014;volume=5;issue=2;spage=176;epage=179;aulast=Abuzayed. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
They most commonly show rhabdomyosarcoma, primitive neuroectodermal tumor, enteric adenocarcinoma, andleukemia transformation.
Ozgur Tanriverdi, Ayca Ersen, Suna Cokmert, Emine Koca, Naki Bulut, Suha Gul, NevinYilmaz 2015, 'The Case of an Elderly Male Patient with Unknown Primary Mucinous Adenocarcinoma withinPresacral Teratoma (Teratoma with Malignant Transformation)', Case Reports in Oncological Medicinehttp://dx.doi.org/10.1155/2015/170479. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Histopathological examination revealed a neuroectodermal tumor of the kidney.
Hamed M El-Darawany 2014, 'Primitive neuroectodermal tumor of the kidney: case report in a 13 year-old boy',Saudi Journal of Medicine and Medical Scienceshttp://www.sjmms.net/article.asp?issn=1658-631X;year=2014;volume=2;issue=3;spage=219;epage=222;aulast=El-Darawany. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Histopathology and immunocytochemical analysis revealed it to be primitive neuroectodermal tumor.
Dhatt Sarvdeep, Dhillon Mandeep, Tripathy Sujit, Goyal Tarun, Jagadeesh V 2010, 'Peripheral primitive neuroectodermal tumor causing cauda equina syndrome with destructionof L5 vertebra', Indian Journal of Orthopaedicshttp://www.ijoonline.com/article.asp?issn=0019-5413;year=2010;volume=44;issue=3;spage=339;epage=341;aulast=Dhatt. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
At present these tumors are classified under primitive neuroectodermal tumor.
Roka Y, Bista P, Sharma G, Adhikari D, Kumar P 2009, 'Frontal recurrence of medulloblastoma five years after excision and craniospinal irradiation',Indian Journal of Pathology and Microbiologyhttp://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=3;spage=383;epage=385;aulast=Roka. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This effect was likely due to lack of actomyosin contractility in superficial neuroectodermal cells.
Chih-Wen Chu, Emma Gerstenzang, Olga Ossipova, Sergei Y. Sokol 2013, 'Lulu Regulates Shroom-Induced Apical Constriction during Neural Tube Closure', PLoS ONE10.1371/journal.pone.0081854. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A biopsy showed melanotic neuroectodermal tumor, and complete resection with negative margins was subsequently achieved.
Hao Tran Kiem, Kim Hoa Nguyen Thi, Phu Tran Xuan, Loi Nguyen Hong, Son Nguyen Huu,Duy Phan Canh, Carlos Rodriguez Galindo, McKay McKinnon 2019, 'Melanotic neuroectodermal tumor of infancy', Journal of Pediatric Surgery Case Reportshttp://www.sciencedirect.com/science/article/pii/S2213576619300934. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The teratomas were positive in 73% in neuroectodermal and / or glandular components.
Daniel J. Heidenberg, Joel H. Barton, Denise Young, Michael Grinkemeyer, Isabell A.Sesterhenn 2012, 'N-cadherin Expression in Testicular Germ Cell and Gonadal Stromal Tumors', Journal of Cancerhttp://www.jcancer.org/v03p0381.htm. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)