This study constitutes the first report on the cytotoxic and nematicidal potential of trichomide cyclodepsipeptides.
Yuan-Ming Zhou, Guang-Lin Ju, Lin Xiao, Xiang-Fei Zhang, Feng-Yu Du 2018, 'Cyclodepsipeptides and Sesquiterpenes from Marine-Derived Fungus Trichotheciumroseum and Their Biological Functions', Marine Drugshttps://www.mdpi.com/1660-3397/16/12/519. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Among terpenes, limonoid triterpenes have been demonstrated to possess interesting insecticidal, nematicidal and antifungal properties.
Trifone D'Addabbo, Sebastiano Laquale, Stella Lovelli, Vincenzo Candido, PinarosaAvato 2014, 'Biocide plants as a sustainable tool for the control of pests and pathogens in vegetablecropping systems', Italian Journal of Agronomyhttps://www.agronomy.it/index.php/agro/article/view/616. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Compounds 2 and 3 showed antifungal activity and compound 2 showed weak nematicidal activity.
Yan-Mei Chen, Yin-He Yang, Xiao-Nian Li, Cheng Zou, Pei-Ji Zhao 2015, 'Diterpenoids from the Endophytic Fungus Botryosphaeria sp. P483 of the Chinese HerbalMedicine Huperzia serrata', Moleculeshttp://www.mdpi.com/1420-3049/20/9/16924. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Other 3-acyltetramic acid analogues showed less than 30% nematicidal activity.
Hyo-Rim Lee, Sung-Chan Lee, Ji-Eun Lee, Seon-Mi Seo, Yong-Chul Jeong, Chan-Sik Jung,Mark G. Moloney, Il-Kwon Park 2017, 'Nematicidal Activity of 3-Acyltetramic Acid Analogues Against Pine Wood Nematode,Bursaphelenchus xylophilus', Moleculeshttps://www.mdpi.com/1420-3049/22/9/1568. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Protoplast fusion was a powerful technique in improving nematicidal activity.
M. S. Abdel-Salam, Hoda H. Ameen, Gaziea M. Soliman, U. S. Elkelany, Amira M. Asar 2018, 'Improving the nematicidal potential of Bacillus amyloliquefaciens and Lysinibacillussphaericus against the root-knot nematode Meloidogyne incognita using protoplast fusiontechnique', Egyptian Journal of Biological Pest Controlhttp://link.springer.com/article/10.1186/s41938-018-0034-3. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Their fusants were tested for their chitinase and nematicidal activity using bioassay and greenhouse experiments.
M. S. Abdel-Salam, Hoda H. Ameen, Gaziea M. Soliman, U. S. Elkelany, Amira M. Asar 2018, 'Improving the nematicidal potential of Bacillus amyloliquefaciens and Lysinibacillussphaericus against the root-knot nematode Meloidogyne incognita using protoplast fusiontechnique', Egyptian Journal of Biological Pest Controlhttp://link.springer.com/article/10.1186/s41938-018-0034-3. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Only compound 18 showed strong nematicidal activity against pine wood nematode.
Seon-Mi Seo, Hyo-Rim Lee, Ji-Eun Lee, Yong-Chul Jeong, Hyung-Wook Kwon, Joon-KwanMoon, Mark G. Moloney, Il-Kwon Park 2017, 'Larvicidal and Nematicidal Activities of 3-Acylbarbituric Acid Analogues against AsianTiger Mosquito, Aedes albopictus, and Pine Wood Nematode, Bursaphelenchus xylophilus',Moleculeshttps://www.mdpi.com/1420-3049/22/7/1196. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Honey has exhibited significant anthelmintic, nematicidal and anti-protozoal activities.
Ahmed Gaffer Hegazi, Fayez Mohammed Al Guthami, Ahmed Faiz Al Gethami, Hassan AliEl Fadaly 2017, 'Beneficial Effects of Capparis Spinosa Honey on the Immune Response of Rats Infectedwith Toxoplasma Gundii', Journal of Pharmacopuncturehttp://dx.doi.org/10.3831/KPI.2017.20.015. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Most of the title compounds exhibited moderate nematicidal activities.
Yanjun Xu, Shuqing Wan, Huizhu Yuan, Bo Li, Xiaoli Yang, Yumei Xiao, Zhaohai Qin 2011, 'Design, Synthesis and Antifungal/Insecticidal Evaluation of Novel Cinnamide Derivatives',Moleculeshttp://www.mdpi.com/1420-3049/16/11/8945/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)