a type of polymer defined by regular branches from a central monomer, which give it a tree-like molecular structure
Examples of 'dendrimer' in a sentence
dendrimer
Prepared polyplexes with fluorinated dendrimer showed over 90% cell viability and transfection efficiency.
Ali Oztuna, Hasan Nazir 2018, 'Pentafluoropropionic Anhydride Functionalized PAMAM Dendrimer as miRNA Delivery Reagent',Journal of the Turkish Chemical Society, Section A: Chemistryhttp://dergipark.gov.tr/jotcsa/issue/37193/463855. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The peptide coverage ability of the dendrimer was between ~50% and 65%.
Márquez-Miranda V, Abrigo J, Rivera JC, Araya-Durán I, Aravena J, Simon F, PachecoN, González-Nilo FD, Cabello-Verrugio C 2017, 'The complex of PAMAM-OH dendrimer with Angiotensin (1–7) prevented the disuse-inducedskeletal muscle atrophy in mice', International Journal of Nanomedicinehttps://www.dovepress.com/the-complex-of-pamam-oh-dendrimer-with-angiotensin-1ndash7-prevented-t-peer-reviewed-article-IJN. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The maleimide groups of the dendrimer are sensitive to hydrolysis under basic conditions.
Changsuk Lee, Kun Ji, Eric E. Simanek 2016, 'Functionalization of a Triazine Dendrimer Presenting Four Maleimides on the Peripheryand a DOTA Group at the Core', Moleculeshttp://www.mdpi.com/1420-3049/21/3/335. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The formed dendrimer conjugates were well characterized using different methods.
Mengen Zhang, Jingyi Zhu, Yun Zheng, Rui Guo, Shige Wang, Serge Mignani, Anne-MarieCaminade, Jean-Pierre Majoral, Xiangyang Shi 2018, 'Doxorubicin-Conjugated PAMAM Dendrimers for pH-Responsive Drug Release and Folic Acid-TargetedCancer Therapy', Pharmaceuticshttp://www.mdpi.com/1999-4923/10/3/162. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Organic compounds designed to serve as stable dendrimer cores were developed.
Mikołaj A. Pyziak, Grażyna Bartkowiak, Łukasz Popenda, Stefan Jurga, Grzegorz Schroeder 2017, 'Synthesis of G0 aminopolyol and aminosugar dendrimers, controlled by NMR and MALDITOF mass spectrometry', Designed Monomers and Polymershttp://dx.doi.org/10.1080/15685551.2016.1231048. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Significant differences in nuclear dendrimer penetration were observed for both cell lines.
Uram Ł, Szuster M, Filipowicz A, Gargasz K, Wołowiec S, Wałajtys-Rode E 2015, 'Different patterns of nuclear and mitochondrial penetration by the G3 PAMAM dendrimerand its biotin–pyridoxal bioconjugate BC-PAMAM in normal and cancer cells invitro', International Journal of Nanomedicinehttps://www.dovepress.com/different-patterns-of-nuclear-and-mitochondrial-penetration-by-the-g3--peer-reviewed-article-IJN. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The third generation dendrimer has the better sensitivity than the first and second generations.
Yaowu Sha, Jin-Hui Wang, Qi Zhang 2010, '8-Hydroxyquinoline Dansylates Modified with PAMAM Dendrimer as Fluorescent Fe3+ Sensors',Moleculeshttp://www.mdpi.com/1420-3049/15/5/2962/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Mono-molecular films formed by physical adsorption and dendrimer self-assembly wereprepared on various substrate surfaces.
Takane Imaoka, Noriko Bukeo, Kimihisa Yamamoto 2018, 'Epitaxially Grown Ultra-Flat Self-Assembling Monolayers with Dendrimers', Moleculeshttp://www.mdpi.com/1420-3049/23/2/485. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Time-of-addition assays were performed to determine dendrimer mechanism of action.
David Tyssen, Scott A Henderson, Adam Johnson, Jasminka Sterjovski, Katie Moore, JenniferLa, Mark Zanin, Secondo Sonza, Peter Karellas, Michael P Giannis, Guy Krippner, SteveWesselingh, Tom McCarthy, Paul R Gorry, Paul A Ramsland, Richard Cone, Jeremy R APaull, Gareth R Lewis, Gilda Tachedjian 2010, 'Structure activity relationship of dendrimer microbicides with dual action antiviralactivity.', PLoS ONEhttp://europepmc.org/articles/PMC2925893?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Two systems were studied consisting of one second-generation lysine dendrimer and16 tetrapeptides.
D. N. Khamidova, �. V. Popovа, V. V. Bezrodny, S. E. Mikhtanyuk, E. V. Popova, I.M. Neelov, F. Leermakers 2018, 'COMPUTER MODELING OF INTERACTION OF LYSINE DENDRIMER WITH EPITHALON PEPTIDES', Naučno-tehničeskij Vestnik Informacionnyh Tehnologij, Mehaniki i Optikihttp://ntv.ifmo.ru/file/article/17944.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)