of, pertaining to, or characterized by a pathological change in the function or form of a cell, leading to its death
Word origin
[1960–65; cyto- + -pathic]This word is first recorded in the period 1960–65. Other words that entered Englishat around the same time include: Pap test, disco, pop art, proxemics, tag questioncyto- is a combining form meaning “cell,” used in the formation of compound words. Otherwords that use the affix cyto- include: cytochemistry, cytopathogenic, cytosol, cytotaxonomy, cytotropic
Examples of 'cytopathic' in a sentence
cytopathic
At 6, 24, 48, and 72 hours post-infection (hpi), cytopathic effects were observed.
Kidsadagon Pringproa, Ruttachuk Rungsiwiwut, Rachod Tantilertcharoen, Reunkeaw Praphet,Kamthorn Pruksananonda, Wolfgang Baumgärtner, Roongroje Thanawongnuwech 2015, 'Tropism and Induction of Cytokines in Human Embryonic-Stem Cells-Derived Neural Progenitorsupon Inoculation with Highly- Pathogenic Avian H5N1 Influenza Virus', PLOS ONE10.1371/journal.pone.0135850. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Of the cultured samples, 28% (17/60) showed cytopathic effect compatible with enterovirus.
S. L. Grenón, M. L. Robledo, M. H. Von Specht, D. M. Cisterna, C. L. Lema, M.C. Freire 2008, 'Brote epidémico de meningitis viral causado por echovirus tipo 4 en la provincia deMisiones Outbreak of viral meningitis caused by echovirus type 4 in Misiones province',Revista Argentina de Microbiologíahttp://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-75412008000100009. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Replication was obtained with all the studied viruses and cytopathic effect was observed with some.
Luiz Tadeu Moraes Figueiredo 1990, 'Uso de células de Aedes albopictus C6/36 na propagação e classificação de arbovírusdas famílias Togaviridae, Flaviviridae, Bunyaviridae e Rhabdoviridae', Revista da Sociedade Brasileira de Medicina Tropicalhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821990000100003. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Moreover, cytopathic effects were observed in 8 of the cell lines tested.
Kelli L Barr, Benjamin D Anderson, Dhani Prakoso, Maureen T Long 2016, 'Working with Zika and Usutu Viruses In Vitro.', PLoS Neglected Tropical Diseaseshttp://europepmc.org/articles/PMC4991799?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A 25% cytopathic effect was observed after 48 hours and 100% after 96 hours.
Figueiredo Cristina A, Oliveira Maria I, Curti Suely P, Cruz Aurea S, Moreira Eliane,Afonso Ana MS, Salles-Gomes Luís Florêncio de 2000, 'RC-IAL cell line: sensitivity of rubella virus grow', Revista de Saúde Públicahttp://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0034-89102000000400007. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
No cytopathic effect was observed after 7 days.
Carlos R. Pantoja, Solangel A. Navarro, Jaime Naranjo, Donald V. Lightner, CharlesP. Gerba 2004, 'Nonsusceptibility of Primate Cells to Taura Syndrome Virus', Emerging Infectious Diseaseshttps://wwwnc.cdc.gov/eid/article/10/12/04-0419_article. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Hantavirus infection of endothelial cells leads to increased vascular permeability without a visible cytopathic effect.
Sergey P Morzunov, Svetlana F Khaiboullina, Svetlana F Khaiboullina, Stephen eSt Jeor,Albert A Rizvanov, Vincent C Lombardi, Vincent C Lombardi, Vincent C Lombardi 2015, 'Multiplex analysis of serum cytokines in humans with hantavirus pulmonary syndrome',Frontiers in Immunologyhttp://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00432/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These findings were coincident with nuclear cytopathic effects but without demonstration of cytomegalovirus inclusions.
G.C. dos Santos, E.R. Parra, F.W. Stegun, C.S. Cirqueira, V.L. Capelozzi 2013, 'Immunohistochemical detection of virus through its nuclear cytopathic effect in idiopathicinterstitial pneumonia other than acute exacerbation', Brazilian Journal of Medical and Biological Researchhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001100985&lng=en&tlng=en. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Transcellular impedance decreased for epithelial monolayers, but not endothelial monolayers, coinciding with cytopathic effect.
Jillian M. Carr, Liam M. Ashander, Julie K. Calvert, Yuefang Ma, Amanda Aloia, GustavoG. Bracho, Soon-Phaik Chee, Binoy Appukuttan, Justine R. Smith 2017, 'Molecular Responses of Human Retinal Cells to Infection with Dengue Virus', Mediators of Inflammationhttp://dx.doi.org/10.1155/2017/3164375. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This process causes further cytopathic, and pathological reactions in the host's body.
M. Khorshid, P. Losada-Pérez, G. Wackers, D. Yongabi, F.U. Renner, R. Thoelen, P.Wagner 2017, 'Real-time monitoring of interactions between Ebola fusion peptide and solid-supportedphospholipid membranes: Effect of peptide concentration and layer geometry', Physics in Medicinehttp://www.sciencedirect.com/science/article/pii/S2352451017300033. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)