curled hairlike processes on the surface of the bacterium Escherichia coli by means of which the bacterium adheres to and infects wounds
Word origin
C20: from curl(ed) (pil)i
Examples of 'curli' in a sentence
curli
This suggests that some genera may utilize alternative regulatory pathways for curli expression.
Morten S. Dueholm, Mads Albertsen, Daniel Otzen, Per Halkjær Nielsen 2012, 'Curli Functional Amyloid Systems Are Phylogenetically Widespread and Display LargeDiversity in Operon and Protein Structure', PLoS ONE10.1371/journal.pone.0051274. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Curli are bacterial functional amyloids that have gained interest as self-assembling biomaterial for biotechnology applications.
Xiuhai Mao, Ke Li, Mengmeng Liu, Xinyu Wang, Tianxin Zhao, Bolin An, Mengkui Cui,Yingfeng Li, Jiahua Pu, Jiang Li, Lihua Wang, Timothy K. Lu, Chunhai Fan, Chao Zhong 2019, 'Directing curli polymerization with DNA origami nucleators', Nature Communicationshttp://link.springer.com/article/10.1038/s41467-019-09369-6. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The bacterial amyloid curli functions in bacterial adherence and enhances the formation of biofilms.
Steven G. Biesecker, Lauren K. Nicastro, R. Paul Wilson, Çağla Tükel 2018, 'The Functional Amyloid Curli Protects Escherichia coli against Complement-MediatedBactericidal Activity', Biomoleculeshttp://www.mdpi.com/2218-273X/8/1/5. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Curli fibrils are considered the most important virulence factor in these bacteria.
Majid Akbari, Bita Bakhshi, Shahin Najar Peerayeh, Mehrdad Behmanesh 2015, 'Detection of Curli Biogenesis Genes Among Enterobacter cloacae Isolated From BloodCultures', International Journal of Enteric Pathogenshttp://enterpathog.abzums.ac.ir/PDF/ijep-3-28413.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We discovered that more than three hundred gene products modulated curli production.
Daniel R. Smith, Janet E. Price, Peter E. Burby, Luz P. Blanco, Justin Chamberlain,Matthew R. Chapman 2017, 'The Production of Curli Amyloid Fibers Is Deeply Integrated into the Biology of Escherichiacoli', Biomoleculeshttps://www.mdpi.com/2218-273X/7/4/75. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Variations in the genetic organization of curli genes are also seen among different bacterial genera.
Morten S Dueholm, Mads Albertsen, Daniel Otzen, Per Halkjær Nielsen 2012, 'Curli functional amyloid systems are phylogenetically widespread and display largediversity in operon and protein structure.', PLoS ONEhttp://europepmc.org/articles/PMC3521004?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This review offers a combined perspective on these first mechanistic insights into the curli system.
Stephen eMatthews, Jonathan eTaylor 2015, 'New insight into the molecular control of bacterial functional amyloids', Frontiers in Cellular and Infection Microbiologyhttp://journal.frontiersin.org/Journal/10.3389/fcimb.2015.00033/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Our results suggest that curli and cellulose exhibit differential and complementary functions.
Ylva Kai-Larsen, Petra Lüthje, Milan Chromek, Verena Peters, Xiaoda Wang, Asa Holm,Lavinia Kádas, Kjell-Olof Hedlund, Jan Johansson, Matthew R Chapman, Stefan H Jacobson,Ute Römling, Birgitta Agerberth, Annelie Brauner 2010, 'Uropathogenic Escherichia coli modulates immune responses and its curli fimbriae interactwith the antimicrobial peptide LL-37.', PLoS Pathogenshttp://europepmc.org/articles/PMC2908543?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Curli fimbriae and cellulose are two basic structural components of the rdar morphotype.
Milanov Dubravka S., Prunić Bojana Z., Velhner Maja J., Pajić Marko Lj., ČabarkapaIvana S. 2015, 'RDAR morphotype: A resting stage of some Enteroba cteriaceae', Food and Feed Researchhttp://scindeks-clanci.ceon.rs/data/pdf/2217-5369/2015/2217-53691501043M.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Curli fimbriae enable initial surface adhesion and intercellular aggregation of bacteria, whilst the cellulose (and other exopolysaccharides) promotes intercellular interactions.
Milanov Dubravka S., Prunić Bojana Z., Velhner Maja J., Pajić Marko Lj., ČabarkapaIvana S. 2015, 'RDAR morphotype: A resting stage of some Enteroba cteriaceae', Food and Feed Researchhttp://scindeks-clanci.ceon.rs/data/pdf/2217-5369/2015/2217-53691501043M.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)