an abnormal immunoglobulin, present in the blood in certain diseases, that precipitates below about 10°C, obstructing small blood vessels in the fingers and toes
Examples of 'cryoglobulin' in a sentence
cryoglobulin
Cryoglobulin prevalence and level drop with time as patients recover, spontaneously or after short-term corticotherapy.
Manuela Oliver, Marc Grandadam, Catherine Marimoutou, Christophe Rogier, ElisabethBotelho-Nevers, Hugues Tolou, Jean-Luc Moalic, Philippe Kraemer, Marc Morillon, Jean-JacquesMorand, Pierre Jeandel, Philippe Parola, Fabrice Simon 2009, 'Persisting mixed cryoglobulinemia in Chikungunya infection.', PLoS Neglected Tropical Diseaseshttp://europepmc.org/articles/PMC2629124?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A serum cryoglobulin test was negative but perinuclear antineutrophilic cytoplasmic antibody test was positive.
Rodrigo Damith, Perera Ruwan, de Silva Janaka 2012, 'Classic polyarteritis nodosa associated with hepatitis C virus infection: a case report',Journal of Medical Case Reportshttp://www.jmedicalcasereports.com/content/6/1/305. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The exact prognostic value of cryoglobulin levels has yet to be determined.
Manuela Oliver, Marc Grandadam, Catherine Marimoutou, Christophe Rogier, ElisabethBotelho-Nevers, Hugues Tolou, Jean-Luc Moalic, Philippe Kraemer, Marc Morillon, Jean-JacquesMorand, Pierre Jeandel, Philippe Parola, Fabrice Simon 2009, 'Persisting mixed cryoglobulinemia in Chikungunya infection.', PLoS Neglected Tropical Diseaseshttp://europepmc.org/articles/PMC2629124?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
If the cryoglobulin precipitates rapidly, aggregated cryoglobulin particles may be interpreted as blood cells.
Geara Abdallah, El-Imad Badiaa, Baz Walid, Odaimi Marcel, El-Sayegh Suzanne 2009, 'Pseudoleukocytosis secondary to hepatitis C-associated cryoglobulinemia: a case report',Journal of Medical Case Reportshttp://www.jmedicalcasereports.com/content/3/1/91. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Vasculitic lesions and livedo reticularis of the legs showed higher prevalence in cryoglobulin-positive than in cryoglobulin-negative patients.
Doaa Salah Hegab, Mohammed Abd El Rahman Sweilam 2015, 'Cryoglobulinaemia in Egyptian Patients with Extrahepatic Cutaneous Manifestationsof Chronic Hepatitis C Virus Infection', Dermatology Research and Practicehttp://dx.doi.org/10.1155/2015/182609. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Cryoglobulin level was determined by spectrophotometry.
O.P. Mashko, E.V. Riabokon, T.E. Onischenko, E.A. Furyk 2016, 'Interrelation of Immunological and Clinic-Morphological Parameters in Patients withChronic Hepatitis C Depending on Mixed Cryoglobulinemia', Aktualʹnaâ Infektologiâhttp://ai.zaslavsky.com.ua/article/view/77666. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
After transplantation, the cryoglobulin concentration was continuously monitored, and plasmapheresis and rituximab infusion were performed as appropriate.
Tomomichi Kasagi, Hironobu Nobata, Kaori Ikeda, Shogo Banno, Yasuhiko Ito 2018, 'Successful renal transplantation to a recipient with type II cryoglobulinemia: a casereport', BMC Nephrologyhttp://link.springer.com/article/10.1186/s12882-018-0966-6. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)