| 释义 |
prionpri‧on /ˈpraɪɒn, ˈpriː- $ -ɑːn/ noun [countable]   prionOrigin: 1900-2000 proteinaceous ‘containing protein’ (19-21 centuries) + infectious particle - A normal gene produces a normal protein, then something goes wrong and the body starts turning out prions.
- Both patients described were heterozygous for the missense mutation at codon 200 of the prion protein gene.
- Computer models are used to create three-dimensional models of prions, helping scientists understand the structural transformation they undergo to turn deadly.
- Healthy proteins, which have not met up with prions, reside quietly in the membranes of nerve cells in the brain.
- No one has been able to create purified prions in a system that would rule out the presence of viruses.
- There are three human prion diseases and four main prion diseases of animals.
NOUN► disease· There are three human prion diseases and four main prion diseases of animals.· Accumulating data indicate that heterozygosity at codon 129 plays an important part in the phenotypic expression of familial prion diseases. ► protein· Both patients described were heterozygous for the missense mutation at codon 200 of the prion protein gene.· Prusiner warned that prion proteins could jump from one species to another, a controversial theory now gaining acceptance.· Design - Screening study of patients suspected clinically to have Creutzfeldt-Jakob disease and other neurodegenerative diseases by prion protein gene analysis. a very small piece of protein that is thought to cause some brain diseases such as BSE |