colonicco‧lon‧ic /kəˈlɒnɪk $ -ˈlɑː-/ adjective 
Examples
ExamplesEXAMPLES FROM THE CORPUS
Collocations- Correlation with platelet count was particularly good in colonic disease.
- Figure 2 illustrates lysozyme mRNA in a colonic biopsy specimen from a patient with longstanding ulcerative colitis.
- In colonic neuropathies contractions were present, but their gastrocolonic response was absent and there were fewer HAPCs.
- The release of colonic regulatory peptides by bile salts does make physiological sense.
- The six children with no colonic contractions had a hollow visceral myopathy and constipation.
- The transit time in these patients was accelerated by a laxative, metoclopramide, and colonic lavage.
- There have been no extensive studies of xenobiotic metabolising enzyme expression in colonic adenomas.
COLLOCATIONS FROM THE CORPUSNOUN► biopsy
relating to the colon· The patients were given supplementation for one month and colonic biopsy specimens were taken before and at the end of the trial.· Figure 2 illustrates lysozyme mRNA in a colonic biopsy specimen from a patient with longstanding ulcerative colitis.· In colonic biopsy specimens from normal and colitic controls inappropriate staining is less evident.
► cancer· Therefore, of 180 patients eligible for colonic cancer surveillance in ulcerative colitis 160 were entered into the programme.· Invitro, high extracellular calcium concentrations inhibit the proliferation of human colonic epithelial cells and several colonic cancer cell lines.· A reduced fibre content of the diet on its own might be an important contributor to the development of colonic cancer.· Of these 25 remain well; 13 ar unaccounted for, and one died from colonic cancer.
► carcinoma· The most important condition to exclude is colonic carcinoma.· The colonic carcinomas were staged using Dukes's classification.· There has been only one report that has identified epoxide hydrolase in colonic carcinomas, by western blot analysis.· Therefore the relation between the ICAM-1 expression and the clinical course seems to be of diagnostic interest for colonic carcinoma.· In conclusion it is justified to examine ICAM-1 expression as a potential prognostic risk factor for colonic carcinoma.· The expression in colonic carcinomas of different forms of glutathione S-transferase has been investigated in several biochemical studies.· Moreover, the same group of xenobiotic metabolising enzymes are probably involved in the development of colonic carcinoma.
► disease· Correlation with platelet count was particularly good in colonic disease.· The change was due to the greater proportion of patients with colonic disease, which in this study had a worse prognosis.· The incidence study has shown that there were more older patients and relatively more patients with colonic disease during the 1980s.· These findings also reflect the higher proportion of elderly patients with colonic disease.· Four patients had only ileal involvement and 16 had ileocolic or colonic disease.
► epithelium· Biochemical studies of normal colonic epithelium have shown that several different xenobiotic metabolising enzymes have a low activity in colonic epithelium.· Results Deposits of formazan were found in the colonic epithelium, vascular endothelium, and infiltrating mononuclear cells.· The colonic epithelium is in continuous contact with potentially carcinogenic compounds, which enter the body usually as part of the diet.· Biochemical studies of normal colonic epithelium have shown that several different xenobiotic metabolising enzymes have a low activity in colonic epithelium.
► motility· Some patterns of normal colonic motility have begun to emerge, but specific abnormalities are yet to be defined.· Most individuals experience the urge to defecate on morning awakening and after meals, when colonic motility is known to peak.· There has recently been a revival of interest in changes in colonic motility in ulcerative colitis.· As well as arousal from sleep and the complex effects of food and polypeptide hormones, neurotransmitters have been shown to affect colonic motility.· Eating is an important stimulus for colonic motility in healthy human subjects.· Although irritable bowel syndrome is commonly believed to be a colonic motility disorder, the evidence supporting this hypothesis is inconsistent.
► mucosa· Increased reactive oxygen species values in the inflamed colonic mucosa in rats were seen by chemiluminescence.· N-acetyl-5ASA is the major metabolite of 5ASA and the primary site of metabolism is probably the colonic mucosa.· The inflammatory cells were absent in the colonic mucosa of Crohn's disease patients examined in remission.· Examination round to the caecum showed no abnormality and biopsy specimens showed normal colonic mucosa.· We also examined whether upward expansion actually occurred in the background colonic mucosa by ex vivo autoradiography.· Ultrastructural changes in colonic mucosa consistent with increased absorption have been described in ulcerative colitis, in both affected and unaffected areas.· These cells infiltrate into the colonic mucosa and are abundant during the active phase of colitis.· We used the reduction of nitroblue tetrazolium to detect the generation of superoxide in inflamed colonic mucosa.
► neoplasia· More recently a series of anecdotal reports suggested that colonic neoplasia might be missed in patients with upper gastrointestinal symptoms or lesions.· Biopsy specimens of normal colon were obtained from patients without any evidence of colonic neoplasia.
► transit· Formulae have been devised to measure segmental colonic transit with radio-opaque shapes.