Fraught with destiny; fateful. Often with mixture of 6 or 7.

That slays or kills. Also transferred and in figurative context.

That kills or deprives of life. literal and figurative.

also dispatching-sheet n. (see quot.).

Having the quality of dispatching or making away with expeditiously. Obsolete.

Of a deadly nature; deadly, fatal.

That commits murder; murderous; involving or suggestive of murder. Also figurative.

That martyrs someone. In extended use: that causes extreme suffering, anguish, etc.