transitive. To infect (a person) with the pox (usually with syphilis). Also figurative: to ruin, destroy. Also with up.

transitive. slang. In oaths and asseverations. Expressing annoyance, hatred, dismissal, etc. Chiefly in optative with no subject expressed. Cf. damn…

Frequently used with euphemistic force. figurative. Also used as a coarse expletive. Cf. fuck, v. 4.

transitive. In oaths and imprecations (chiefly in optative with no subject expressed): expressing annoyance, hatred, dismissal, etc. Cf. damn, v. 6…

Used profanely in imprecations and exclamations. Cf. fuck, v. 4, shag, v.4 1.

Used in coarse expressions of contempt or defiance. Cf. fuck, v. 4; stuffed, adj. 6.

transitive. Esp. in African-American usage: used (chiefly in optative subjunctive and with no subject expressed) to express emphatic rejection…

transitive. = fuck, v. 4. Also (in passive): to be put into a difficult or hopeless situation, to be in trouble.