transitive (reflexive). To become excited or angry; to be perturbed. Also: to stir or rouse oneself to action. Obsolete.

transitive. To fill with enthusiasm, passion, anger, etc.; to stimulate, excite.

transitive. To act on the feelings of; to agitate, excite; to move, rouse into or to a specified emotional state, esp. excitement. Also reflexive…

transitive (reflexive). To excite or arouse oneself. Obsolete.

Usually as hyped past participle or participial adjective (const. up) stimulated, worked up (as if from the effects of a hypodermic injection).