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1821 Monthly Gaz. Health 6 930 Some French physicians fancy that they have ascertained that the most active principles of opium reside in two substances, namely, Narcotine and Morphine.

1823 C. T. Haden tr. F. Magendie Formulary New Remedies 28 If a grain of narcotine, dissolved in oil, be given to dogs, it produces a state of stupor.

1876 J. Harley Royle's Man. Materia Med. (ed. 6) 762 A solution of narcotine and hydrochlorate of papaverine.

1914 Jrnl. Chem. Soc. 105 2087 It is proposed to call the substance melting at 180° β-gnoscopine, reserving the name α-gnoscopine for the compound previously known as gnoscopine or r-narcotine, which melts at 229°.

1923 Nature 17 Feb. 243/2 The ultraviolet absorption spectrum of narcotine is determined by the benzene ring of its molecule.

1953 I. Heilbron & H. M. Bunbury Dict. Org. Compounds (rev. ed.) III. 594/2 β-Narcotine... Stereoisomer of α-narcotine.

1968 I. L. Finar Org. Chem. (ed. 4) II. ii. 78 Ferreira (1953) has partially resolved (±)-narcotine..without the use of optically active reagents.

1996 Planta Medica 62 544 The detection of urinary narcotine, papaverine, or thebaine may be utilized to differentiate poppy seed consumption from illicit codeine, morphine, or heroin use.