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单词 xanthoma
释义

xanthoman.

Brit. /zanˈθəʊmə/, U.S. /zænˈθoʊmə/
Forms: Plural xanthomas, xanthomata.
Etymology: < Greek ξανθός yellow + -ωμα (compare sarcoma).
Pathology.
An affection of the skin, characterized by the growth of yellowish patches or tubercles. Also, esp. in modern use, such a patch or tubercle. Frequently with modern Latin adjectives. Also attributive.
ΘΚΠ
the world > health and disease > ill health > a disease > disorders of visible parts > skin disorders > [noun] > disordered pigmentation
melasma1563
orange skin1822
melanopathia1847
xanthosis1853
xanthelasma1867
xanthochroia1867
xanthoderma1867
xanthopathia1867
xanthoma1869
argyria1874
chloasma1877
leucoderma1884
xeroderma pigmentosum1884
hyperchromatosis1886
melanodermia1886
leucodermia1888
hyperchromasia1889
hyperpigmentation1890
hypochromia1890
xanthochromia1894
xanthodermia1900
melanization1927
1869 Jrnl. Cutaneous Med. 3 241 (heading) On xanthoma, or vitiligoidea.
1869 Jrnl. Cutaneous Med. 3 317 After entry into hospital, patches of xanthoma developed in both eyelids.
1874 W. Tay tr. F. Hebra & M. Kaposi On Dis. Skin III. 345 There are two forms of the disease—1st, it occurs in the form of yellow patches—Xanthoma planum..; 2nd, in the form of tubercles—Xanthoma tuberosum.
1877 L. A. Duhring Pract. Treat. Dis. Skin 410 Xanthoma is a connective-tissue new growth, characterized by the formation of yellowish, circumscribed, irregularly shaped..non-indurated patches or tubercles.
1896 N. Walker tr. P. G. Unna Histopathol. Dis. Skin 945 The xanthoma of the eyelid may gradually develop protuberances, without giving up its own peculiar histological character.
1899 T. C. Allbutt et al. Syst. Med. VIII. 484 The chamois-leather-like patches may simulate xanthoma.
1899 T. C. Allbutt et al. Syst. Med. VIII. 896 The so-called ‘xanthoma cell’ is..a fragmented muscle fibre in a state of granulo-fatty degeneration.
1949 R. L. Sutton Handbk. Dis. Skin 385 Tuberous xanthomas are occasionally solitary.
1961 Lancet 12 Aug. 341/2 All her plasma-lipids tended to return to normal values..and her xanthomata completely disappeared.
1968 A. J. Rook et al. Textbk. Dermatol. II. xxxviii. 1229/1 Xanthoma disseminatum is a rare histiocytic proliferative disorder characterized by widespread cutaneous xanthomata..but usually without evidence of systemic disturbance of lipid metabolism.
1974 S. L. Robbins Pathol. Basis Dis. xxx. 1410/1 These xanthomas may be widespread and occur in varied forms, such as xanthoma tuberosum.

Derivatives

xanthomaˈtosis n. a metabolic disorder marked by the accumulation of excess lipid and by the presence of multiple and wide-spread xanthoma.
ΘΚΠ
the world > health and disease > ill health > a disease > disorders of internal organs > metabolic disorders > [noun] > other metabolic disorders
xanthomatosis1900
Tay-Sachs1907
ketosis1917
protein shock1917
hyperinsulinism1924
Niemann–Pick1928
tyrosinosis1932
von Gierke's disease1933
phenylketonuria1935
cystic fibrosis1938
mucoviscidosis1945
cystinosis1949
oxalosis1952
McArdle1957
orotic aciduria1959
PKU1961
sphingolipidosis1962
Reye's syndrome1965
Menkes1969
1900 W. A. N. Dorland Amer. Illustr. Med. Dict. 764/1 Xanthomatosis.
1923 Brit. Jrnl. Dermatol. 35 90 Xanthomatosis is probably a process of infiltration dependent primarily upon hypercholesterolæmia.
1961 Lancet 7 Oct. 802/2 Cases of familial hyper~cholesterolæmic xanthomatosis.
1983 D. J. Weatherall et al. Oxf. Textbk. Med. I. ix. 113/1 The relationship between cerebrotendinous xanthomatosis and spinal cholesterosis..is uncertain.
xanthomatous adj. /-ˈəʊmətəs/ pertaining to or of the nature of xanthoma.
ΘΚΠ
the world > health and disease > ill health > a disease > disorders of visible parts > skin disorders > [adjective] > disordered pigmentation
sallowOE
sallow-coloured1551
sallow-faced1605
melanosed1829
sallow-visaged1853
melasmic1865
melanodermic1890
sallow-looking1892
xanthelasmic1900
xanthomatous1914
1914 Lancet 13 June 1697/1 Xanthomatous nodules in the liver.
This entry has not yet been fully updated (first published 1921; most recently modified version published online December 2021).
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n.1869
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