vinblastinen.

/vɪnˈblastiːn/

Etymology: < modern Latin Vin-ca, former generic name (see periwinkle n.¹) + leuco- comb. form + -ine suffix⁵.

Pharmacology.

A cytotoxic alkaloid, C₄₆H₅₈N₄O₉, obtained from the periwinkle Catharanthus roseus and administered intravenously (usually as the sulphate) in the treatment of lymphomas and other cancers. Cf. vincristine n.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for cancer or leukemia

amethopterin1948

Myleran1952

Laetrile1953

thioguanine1953

thioTEPA1953

mercaptopurine1954

methotrexate1955

busulfan1956

chlorambucil1956

cyclophosphamide1960

vinblastine1962

vincristine1962

levamisole1969

vinca alkaloid1970

doxorubicin1971

tamoxifen1972

Airol1974

trastuzumab1997

thiotepa-

1962 M. R. Karon et al. in Pediatrics XXX. 791/1 Several alkaloids were subsequently isolated from the crude extract [of Vinca rosea], two of which, leurosine and vinblastine (formerly called vincaleukoblastine), markedly inhibited this tumour.

1974 Nature 15 Mar. 239/1 The alkaloids colchicine and vinblastine interfere with the assembly of microtubules, yet they also affect several properties of the surface membrane of animal cells.

1983 D. J. Weatherall et al. Oxf. Textbk. Med. II. xix. 96/1 Vincristine..is preferable to vinblastine..in the treatment of leukaemia.

This entry has not yet been fully updated (first published 1986; most recently modified version published online March 2021).

单词	vinblastine
释义	vinblastinen. /vɪnˈblastiːn/ Etymology: < modern Latin Vin-ca, former generic name (see periwinkle n.¹) + leuco- comb. form + -ine suffix⁵. Pharmacology. A cytotoxic alkaloid, C₄₆H₅₈N₄O₉, obtained from the periwinkle Catharanthus roseus and administered intravenously (usually as the sulphate) in the treatment of lymphomas and other cancers. Cf. vincristine n. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for cancer or leukemia amethopterin1948 Myleran1952 Laetrile1953 thioguanine1953 thioTEPA1953 mercaptopurine1954 methotrexate1955 busulfan1956 chlorambucil1956 cyclophosphamide1960 vinblastine1962 vincristine1962 levamisole1969 vinca alkaloid1970 doxorubicin1971 tamoxifen1972 Airol1974 trastuzumab1997 thiotepa- 1962 M. R. Karon et al. in Pediatrics XXX. 791/1 Several alkaloids were subsequently isolated from the crude extract [of Vinca rosea], two of which, leurosine and vinblastine (formerly called vincaleukoblastine), markedly inhibited this tumour. 1974 Nature 15 Mar. 239/1 The alkaloids colchicine and vinblastine interfere with the assembly of microtubules, yet they also affect several properties of the surface membrane of animal cells. 1983 D. J. Weatherall et al. Oxf. Textbk. Med. II. xix. 96/1 Vincristine..is preferable to vinblastine..in the treatment of leukaemia. This entry has not yet been fully updated (first published 1986; most recently modified version published online March 2021). < n.1962
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