variolationn.

Brit.

/ˌvɛːrɪəˈleɪʃn/, U.S.

/ˌvɛriəˈleɪʃ(ə)n/

Origin: Formed within English, by derivation. Etymons: variolate v., -ion suffix¹.

Etymology: < variolate v. + -ion suffix¹. Perhaps compare post-classical Latin variolatio (occasionally attested in the 16th and 18th centuries in uncertain sense, perhaps ‘formation of variolous matter’ or ‘infection with smallpox’).

Medicine. Now historical.

Inoculation of material from the pocks of variola (smallpox); an instance of this. In early use also: †the formation of variolous matter or of pocks (obsolete rare).Frequently contrasted with vaccination (see vaccination n. 1).Variolation was used in humans as means of preventing smallpox, and was also performed in cows and other animals for experimental purposes and to produce further material for the procedure.

ΘΚΠ

the world > health and disease > healing > medical treatment > immunoprophylaxis > [noun] > immunization > inoculation or vaccination > against smallpox

inoculation1714

engrafting1717

engraftment1724

variolation1799

vaccination1800

vaccinating1801

vacciolation1804

cow-poxingc1815

variolization1871

1799 W. Woodville Rep. Series Inoculations Variolæ Vaccinæ 145 Hence it appears, that the process of variolation in the natural and in the inoculated Small-pox, is different.

1804 Philos. Mag. 19 94 A number of subjects who had undergone vaccination in the year 1800..have been submitted to the test or counter-proof, variolation.

1810 Edinb. Rev. 15 340 It [sc. vaccination] has been adopted by millions who never would have submitted to variolation.

1852 London Jrnl. Med. 4 817 Successful experiments on the variolation of the cow, and the production of vaccine lymph.

1896 T. C. Allbutt et al. Syst. Med. I. 559 The practice of variolation, which was revived and introduced into Great Britain by Lady Mary Wortley Montagu.

1903 Proc. Royal Soc. 1902–3 71 132 In his first series of variolations of the monkey, the small-pox lymph employed was obtained from a Javanese child.

1954 G. P. Gladstone & E. P. Abraham in H. W. Florey Lect. Gen. Pathol. xxiii. 407 The practice of variolation, as it was called, is probably very old and no one knows its origin.

1992 F. McLynn Hearts of Darkness xi. 246 They also practised variolation similar to the Ashanti method—inoculating with pus from the pock of a victim.

2011 Providence (Rhode Island) Jrnl. (Nexis) 4 July 7 Jefferson was one of this nation's most vigorous proponents of variolation as protection against smallpox.

This entry has been updated (OED Third Edition, June 2014; most recently modified version published online December 2021).

单词	variolation
释义	variolationn. Brit. /ˌvɛːrɪəˈleɪʃn/, U.S. /ˌvɛriəˈleɪʃ(ə)n/ Origin: Formed within English, by derivation. Etymons: variolate v., -ion suffix¹. Etymology: < variolate v. + -ion suffix¹. Perhaps compare post-classical Latin variolatio (occasionally attested in the 16th and 18th centuries in uncertain sense, perhaps ‘formation of variolous matter’ or ‘infection with smallpox’). Medicine. Now historical. Inoculation of material from the pocks of variola (smallpox); an instance of this. In early use also: †the formation of variolous matter or of pocks (obsolete rare).Frequently contrasted with vaccination (see vaccination n. 1).Variolation was used in humans as means of preventing smallpox, and was also performed in cows and other animals for experimental purposes and to produce further material for the procedure. ΘΚΠ the world > health and disease > healing > medical treatment > immunoprophylaxis > [noun] > immunization > inoculation or vaccination > against smallpox inoculation1714 engrafting1717 engraftment1724 variolation1799 vaccination1800 vaccinating1801 vacciolation1804 cow-poxingc1815 variolization1871 1799 W. Woodville Rep. Series Inoculations Variolæ Vaccinæ 145 Hence it appears, that the process of variolation in the natural and in the inoculated Small-pox, is different. 1804 Philos. Mag. 19 94 A number of subjects who had undergone vaccination in the year 1800..have been submitted to the test or counter-proof, variolation. 1810 Edinb. Rev. 15 340 It [sc. vaccination] has been adopted by millions who never would have submitted to variolation. 1852 London Jrnl. Med. 4 817 Successful experiments on the variolation of the cow, and the production of vaccine lymph. 1896 T. C. Allbutt et al. Syst. Med. I. 559 The practice of variolation, which was revived and introduced into Great Britain by Lady Mary Wortley Montagu. 1903 Proc. Royal Soc. 1902–3 71 132 In his first series of variolations of the monkey, the small-pox lymph employed was obtained from a Javanese child. 1954 G. P. Gladstone & E. P. Abraham in H. W. Florey Lect. Gen. Pathol. xxiii. 407 The practice of variolation, as it was called, is probably very old and no one knows its origin. 1992 F. McLynn Hearts of Darkness xi. 246 They also practised variolation similar to the Ashanti method—inoculating with pus from the pock of a victim. 2011 Providence (Rhode Island) Jrnl. (Nexis) 4 July 7 Jefferson was one of this nation's most vigorous proponents of variolation as protection against smallpox. This entry has been updated (OED Third Edition, June 2014; most recently modified version published online December 2021). < n.1799
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