vaccinoidadj.n.

Brit.

/ˈvaksᵻnɔɪd/, U.S.

/ˈvæksəˌnɔɪd/

Origin: Formed within English, by derivation; modelled on a German lexical item. Etymons: vaccine n., -oid suffix.

Etymology: < vaccine n. + -oid suffix, after German Vaccinoid (1831 or earlier).Compare French vaccinoïde, adjective (1839 or earlier) and noun (1826 or earlier).

Medicine.

A. adj.

Originally: designating the disease produced by revaccination against smallpox, and the skin lesions characteristic of this. In later use: spec. designating a type of reaction to inoculation of vaccinia virus that is seen in persons with partial immunity to the virus, and is characterized by milder symptoms and a more rapid course than the reaction occurring in a person with no immunity.

ΚΠ

1839 Brit. & Foreign Med. Rev. 7 207 In the district of Waiblingen the progress of the vaccinoid affection was observed to be quicker than the genuine cow-pox; usually there was itching in the wound a few hours after the revaccination.

1866 A. Flint Treat. Princ. Med. 782 Partial success [of revaccination], as shown by imperfect or vaccinoid vesicles, is still more common.

1913 Calif. State Jrnl. Med. 11 291/1 Before the vaccinoid reaction had reached its height she was revaccinated a fourth time.

1953 R. W. Fairbrother Text-bk. Bacteriol. (ed. 7) xxxii. 408 In immunized individuals, successful re-vaccination is followed by three types of reaction depending on the immunity state of the individual:..(2) accelerated or vaccinoid reaction, in which there is a mild form of reaction, complete in 8–10 days; this indicates a moderate degree of immunity.

2002 Amer. Jrnl. Nursing 102 28/1 Most people who receive the smallpox vaccine will have one of three normal reactions: the primary and vaccinoid responses, both of which are often called ‘takes’, and the immune response, referred to as a ‘no-take’.

B. n.

Originally: vaccinoid disease; an instance or case of this. In later use: spec. a vaccinoid reaction. Now rare.

ΚΠ

1849 Summary Trans. Coll. Physicians Philadelphia 1846–9 2 47 But still the local disease [after re-vaccination] was always a modification of the true vaccine; a mere vaccinoid.

1866 A. Flint Treat. Princ. Med. 781 Incomplete vaccinia, vaccinoid, as it is termed by Trousseau, is evidenced by the vesicles being developed more quickly and progressing to desiccation more rapidly.

1913 Calif. State Jrnl. Med. 11 290/2 Clinically we see a scale of appearances ranging from ‘early reaction’ and ‘torpid early reaction’ through many types of ‘accelerated reaction’ or vaccinoid.

1944 Jrnl. Hygiene 43 340/2 In revaccination the routine use of one insertion only may result in a certain number of semi-immunes (vaccinoids) being erroneously reported as immunes.

This entry has been updated (OED Third Edition, March 2022).

单词	vaccinoid
释义	vaccinoidadj.n. Brit. /ˈvaksᵻnɔɪd/, U.S. /ˈvæksəˌnɔɪd/ Origin: Formed within English, by derivation; modelled on a German lexical item. Etymons: vaccine n., -oid suffix. Etymology: < vaccine n. + -oid suffix, after German Vaccinoid (1831 or earlier).Compare French vaccinoïde, adjective (1839 or earlier) and noun (1826 or earlier). Medicine. A. adj. Originally: designating the disease produced by revaccination against smallpox, and the skin lesions characteristic of this. In later use: spec. designating a type of reaction to inoculation of vaccinia virus that is seen in persons with partial immunity to the virus, and is characterized by milder symptoms and a more rapid course than the reaction occurring in a person with no immunity. ΚΠ 1839 Brit. & Foreign Med. Rev. 7 207 In the district of Waiblingen the progress of the vaccinoid affection was observed to be quicker than the genuine cow-pox; usually there was itching in the wound a few hours after the revaccination. 1866 A. Flint Treat. Princ. Med. 782 Partial success [of revaccination], as shown by imperfect or vaccinoid vesicles, is still more common. 1913 Calif. State Jrnl. Med. 11 291/1 Before the vaccinoid reaction had reached its height she was revaccinated a fourth time. 1953 R. W. Fairbrother Text-bk. Bacteriol. (ed. 7) xxxii. 408 In immunized individuals, successful re-vaccination is followed by three types of reaction depending on the immunity state of the individual:..(2) accelerated or vaccinoid reaction, in which there is a mild form of reaction, complete in 8–10 days; this indicates a moderate degree of immunity. 2002 Amer. Jrnl. Nursing 102 28/1 Most people who receive the smallpox vaccine will have one of three normal reactions: the primary and vaccinoid responses, both of which are often called ‘takes’, and the immune response, referred to as a ‘no-take’. B. n. Originally: vaccinoid disease; an instance or case of this. In later use: spec. a vaccinoid reaction. Now rare. ΚΠ 1849 Summary Trans. Coll. Physicians Philadelphia 1846–9 2 47 But still the local disease [after re-vaccination] was always a modification of the true vaccine; a mere vaccinoid. 1866 A. Flint Treat. Princ. Med. 781 Incomplete vaccinia, vaccinoid, as it is termed by Trousseau, is evidenced by the vesicles being developed more quickly and progressing to desiccation more rapidly. 1913 Calif. State Jrnl. Med. 11 290/2 Clinically we see a scale of appearances ranging from ‘early reaction’ and ‘torpid early reaction’ through many types of ‘accelerated reaction’ or vaccinoid. 1944 Jrnl. Hygiene 43 340/2 In revaccination the routine use of one insertion only may result in a certain number of semi-immunes (vaccinoids) being erroneously reported as immunes. This entry has been updated (OED Third Edition, March 2022). < adj.n.1839
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