单词 | uncoupler |
释义 | > as lemmasunˈcoupler unˈcoupler n. spec. in Biochemistry, any agent that causes the uncoupling of oxidative phosphorylation. ΘΚΠ the world > matter > chemistry > organic chemistry > chemical processes or reactions > biochemical reactions and processes > [noun] > uncoupling > uncoupling agent uncoupler1956 uncoupling agent1956 1705 Stevens ii An Uncoupler, desuñidor. 1956 Science 22 June 1107/1 The factor specifically inhibits phosphorylation without affecting the oxidation of β-hydroxybutyrate and thus simulates the action of 2,4-dinitrophenol and other known uncouplers. 1976 Sci. Amer. June 44/3 Then we tried uncouplers: agents that allow electron transport to proceed but that in effect disconnect it from phosphorylation and thus from the ATP synthesis it usually accomplishes. 1979 Nature 8 Feb. 486/1 We have found that the rapid efflux of Ca2+ brought about by collapse of the membrane potential by uncouplers or antimycin A..is not affected by tetracaine. < as lemmas |
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