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单词 uncoupler
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unˈcoupler
unˈcoupler n. spec. in Biochemistry, any agent that causes the uncoupling of oxidative phosphorylation.
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the world > matter > chemistry > organic chemistry > chemical processes or reactions > biochemical reactions and processes > [noun] > uncoupling > uncoupling agent
uncoupler1956
uncoupling agent1956
1705 Stevens ii An Uncoupler, desuñidor.
1956 Science 22 June 1107/1 The factor specifically inhibits phosphorylation without affecting the oxidation of β-hydroxybutyrate and thus simulates the action of 2,4-dinitrophenol and other known uncouplers.
1976 Sci. Amer. June 44/3 Then we tried uncouplers: agents that allow electron transport to proceed but that in effect disconnect it from phosphorylation and thus from the ATP synthesis it usually accomplishes.
1979 Nature 8 Feb. 486/1 We have found that the rapid efflux of Ca2+ brought about by collapse of the membrane potential by uncouplers or antimycin A..is not affected by tetracaine.
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