tubocurarinen.
/tjuːbəʊˈkjʊərəriːn/ Pharmacology.
An isoquinoline alkaloid that is the active ingredient of tube curare and whose chloride, C37H42Cl2N2O6, is used as a muscle relaxant.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > depressor of muscular action > specific drugs
tubocurarine1898
Anectine1950
succinylcholine1950
suxamethonium1953
the world > health and disease > healing > medicines or physic > medicines for specific purpose > anaesthetic > [noun] > general > specific drugs
common ether1675
laughing gas1819
chloral1838
chloroform1838
urethane1838
ether1847
letheon1847
kerosolene1861
gas1868
pental1891
tubocurarine1898
chloretone1899
hedonal1900
Avertin1927
Evipan1932
Pentothal1935
Trilene1935
hexobarbitone sodium1941
hexobarbitone soluble1941
thiopentone1945
thiopental sodium1947
fluothane1955
halothane1957
methohexital sodium1958
phencyclidine1959
methohexitone1961
hexobarbitone1962
propanidid1964
etorphine1966
enflurane1971
sodium methohexital1978
1898 Jrnl. Chem. Soc. 74 i. 284 Paracurarine (tubocurarine).
1935 Nature 23 Mar. 470/1 The quaternary alkaloid tubocurarine..has now been crystallised for the first time.
1973 Reader's Digest Apr. 206/1 They paralysed him with 70 milligrams of tubocurarine chloride.
1977 Lancet 19 Mar. 650/2 Three drugs used in clinical anæsthesia consistently cause arterial hypotension in patients with essential hypertension—halothane, d- tubocurarine, and verapamil.
This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018).
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n.1898