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单词 tricarboxylic acid
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tricarboxylic acid
tricarboxylic acid: any acid with three carboxyl groups in each molecule; tricarboxylic acid cycle, the Krebs cycle (see Krebs n.).
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tricarboxylic acid1894
1894 W. H. Perkin & F. S. Kipping Org. Chem. I. xiii. 246 Citric acid is tricarboxylic acid, and..forms three classes of salts.
1938 G. H. Richter Textbk. Org. Chem. xvi. 302 Aconitic acid is an example of an unsaturated tricarboxylic acid.
1945 Jrnl. Biol. Chem. 161 413 (heading) Fatty acid oxidation and the Krebs tricarboxylic acid cycle.
1947 Jrnl. Biol. Chem. 171 446 Tricarboxylic acids may be formed in plants by a process involving the addition of CO2 to an α-ketoglutarate.
1950 Chem. Abstr. 44 1552 (heading) Final stage in biological oxidation processes: Krebs' tricarboxylic acid cycle.
1974 B. A. Newton in K. Elliott et al. Trypanosomiasis & Leishmaniasis (Ciba Symp. No. 20) 299 Some of the changes which occur during the development of T. cruzi, such as the activity of the tricarboxylic acid cycle enzymes.., may only be quantitative changes.
1982 M. S. Olson in T. M. Devlin Textbk. Biochem. vi. 278 Various investigators defined many of the enzymes and di- and tricarboxylic acid intermediates in this pathway, but it was Krebs who pieced together these components in his formulation of the ‘Krebs cycle’.
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